Phosphodiesterase PDE6C: A Potential Drug Target and Biomarker

Target Name: PDE6C

NCBI ID: G5146

PDE6C

Phosphodiesterase PDE6C: A Potential Drug Target and Biomarker

Phosphodiesterase PDE6C (PDE6C) is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the phospholipid biosynthesis pathway, which is involved in the production of phosphatidylcholine, the main component of cell membranes. Lipids such as PTC) and phosphatidylinositol (PIN). Under normal circumstances, PDE6C plays important biological functions within cells, but when it mutates, it may also cause a series of diseases. Currently, researchers are studying the potential of PDE6C in drug development and biomarker applications.

Mutations in PDE6C cause various diseases

Mutations in PDE6C can cause a variety of diseases, including neurological diseases, cardiovascular diseases, and tumors. Mutations in PDE6C can lead to abnormalities in the synthesis of lipids such as phosphatidylcholine and phosphatidylinositol, thereby affecting the composition and function of cell membranes.

Drug development for PDE6C

PDE6C has high potential as a drug target. Because PDE6C is mutated in a variety of diseases, developing drugs for PDE6C could become a new way to treat a variety of diseases. Researchers are exploring the effects of pharmacological intervention with PDE6C in the treatment of neurological diseases, cardiovascular diseases and tumors.

Biomarker applications of PDE6C

PDE6C also has high potential for biomarker applications. The intracellular activity of PDE6C makes it a potential biomarker that can be used to detect disease progression and treatment efficacy. Currently, researchers are exploring the use of PDE6C as a biomarker for diagnosis and treatment of tumors and other diseases.

Biological functions of PDE6C

PDE6C functions in vivo

Protein Name: Phosphodiesterase 6C

Functions: As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP

The "PDE6C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDE6C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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