Phosphodiesterase 7B: A Potential Drug Target (G27115)

Target Name: PDE7B

NCBI ID: G27115

PDE7B

Phosphodiesterase 7B: A Potential Drug Target

Phosphodiesterase 7B (PDE7B) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It plays a crucial role in the regulation of cellular signaling pathways, and is involved in the breakdown of various types of signaling molecules, including cAMP and cGMP.

PDE7B is a potent enzyme that is known to modulate the activity of many different signaling pathways. For example, it has been shown to play a role in the regulation of neural plasticity, the ability of the brain to learn and adapt, and the regulation of cardiovascular function.

One of the unique features of PDE7B is its ability to act as a drug target. This is because of its high expression level in the brain, and its involvement in a wide range of cellular signaling pathways. As a result, PDE7B has been identified as a potential drug target for a variety of neurological and cardiovascular conditions.

One of the key benefits of targeting PDE7B is its potential to modulate the activity of signaling pathways that are involved in a wide range of physiological processes. For example, PDE7B has been shown to play a role in the regulation of neurotransmitter release, which is involved in the transmission of signals from the brain to the rest of the body.

In addition, PDE7B has also been shown to play a role in the regulation of ion channels, which are responsible for the flow of electrical signals through the cells. This is important because changes in the activity of ion channels can have a significant impact on the electrical activity of the cell, and these changes can be involved in a wide range of physiological processes.

Another potential benefit of targeting PDE7B is its ability to modulate the activity of signaling pathways that are involved in the regulation of cellular growth and differentiation. This is important because changes in cellular growth and differentiation can be involved in the development of a wide range of diseases , including cancer.

In addition, PDE7B has also been shown to play a role in the regulation of inflammation, which is a complex process that is involved in the immune response and the regulation of cellular signaling pathways. This is important because changes in inflammation can be involved in the development of a wide range of diseases, including cardiovascular disease and neurological diseases.

Overall, PDE7B is a protein that is involved in a wide range of cellular signaling pathways, and has been shown to play a role in the regulation of neurotransmitter release, ion channels, cellular growth and differentiation, and inflammation. As a result, PDE7B is a potential drug target for a variety of neurological and cardiovascular conditions. Further research is needed to fully understand the role of PDE7B in these processes, and to develop effective treatments for diseases that are caused by changes in its activity.

Protein Name: Phosphodiesterase 7B

Functions: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10814504, PubMed:10872825). May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (PubMed:10814504)

The "PDE7B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDE7B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets