Target Name: PLCD1
NCBI ID: G5333
Review Report on PLCD1 Target / Biomarker Content of Review Report on PLCD1 Target / Biomarker
PLCD1
Other Name(s): NDNC3 | Phospholipase C-III | epididymis secretory sperm binding protein | Phospholipase C-delta-1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (isoform 2) | PLC-III | OTTHUMP00000161383 | PLCD1 variant 1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | PLCD1_HUMAN | Phospholipase C I 1 | phospholipase C delta 1 | Phospholipase C delta 1, transcript variant 1 | PLC-delta-1 | PLCD1 variant 2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (isoform 1) | phospholipase C-III | Phospholipase C delta 1 | phosphoinositide phospholipase C-delta-1 | Phospholipase C delta 1, transcript variant 2 | Phosphoinositide phospholipase C-delta-1 | OTTHUMP00000226936

PLCD1: A Promising Drug Target / Biomarker

Platelet-derived cytosol (PDC) is a protein that is found in the cytoplasm of platelets, which are the smallest cells in the body. PDCs are known for their ability to deliver a variety of molecules to various tissues and organs, including the brain. One of the things that PDCs are able to do is to release and transport proteins, such as growth factors and cytokines, which can have a wide range of effects on the cells and tissues they interact with.

One of the proteins that PDCs are known for delivering is PLCD1. PLCD1 is a protein that is expressed in high levels in the brain and is involved in the regulation of many different processes that are important for brain development and function. While the exact functions of PLCD1 and the mechanisms by which it works are not yet fully understood, research into this protein has the potential to shed light on the many complex processes that are involved in the development and treatment of brain diseases.

Drug Targeting

One of the potential ways to treat brain diseases is through the use of drugs that target specific proteins, such as PLCD1. This approach is based on the idea that by blocking the activity of a protein, it can reduce the effects of the disease and potentially lead to a better outcome.

One of the reasons why PLCD1 is an attractive drug target is that it is involved in many different processes that are important for brain development and function. For example, PLCD1 has been shown to play a role in the regulation of neural stem cell proliferation and differentiation, as well as in the formation of synapses in the brain. Additionally, PLCD1 has been shown to be involved in the regulation of neurotransmitter release and in the modulation of pain perception.

Another potential benefit of targeting PLCD1 is that it is a protein that is expressed in high levels in the brain and is not expressed in other tissues or organs, which makes it a potentially more effective drug target. This is because drugs that are able to specifically target a protein that is expressed in high levels in the brain are less likely to have unintended effects on other tissues or organs.

Biomarker

In addition to its potential as a drug target, PLCD1 is also a potential biomarker for the diagnosis and progression of brain diseases. The ability of PLCD1 to be targeted by drugs suggests that it may be a useful target for the treatment of certain brain diseases. Additionally, the fact that PLCD1 is expressed in high levels in the brain suggests that it may be a useful biomarker for the diagnosis of certain brain diseases, such as neurodegenerative disorders.

Conclusion

In conclusion, PLCD1 is a protein that is expressed in high levels in the brain and is involved in the regulation of many different processes that are important for brain development and function. While the exact functions of PLCD1 are not yet fully understood, research into this protein has the potential to shed light on the many complex processes that are involved in the development and treatment of brain diseases. Additionally, the potential use of PLCD1 as a drug target and biomarker make it an attractive target for future research.

Protein Name: Phospholipase C Delta 1

Functions: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed:9188725). Essential for trophoblast and placental development (By similarity). Binds phosphatidylinositol 4,5-bisphosphate (PubMed:7890667, PubMed:9188725)

The "PLCD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLCD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLCD3 | PLCD4 | PLCE1 | PLCE1-AS2 | PLCG1 | PLCG1-AS1 | PLCG2 | PLCH1 | PLCH2 | PLCL1 | PLCL2 | PLCXD1 | PLCXD2 | PLCXD3 | PLCZ1 | PLD1 | PLD2 | PLD3 | PLD4 | PLD5 | PLD6 | PLEC | PLEK | PLEK2 | PLEKHA1 | PLEKHA2 | PLEKHA3 | PLEKHA4 | PLEKHA5 | PLEKHA6 | PLEKHA7 | PLEKHA8 | PLEKHA8P1 | PLEKHB1 | PLEKHB2 | PLEKHD1 | PLEKHF1 | PLEKHF2 | PLEKHG1 | PLEKHG2 | PLEKHG3 | PLEKHG4 | PLEKHG4B | PLEKHG5 | PLEKHG6 | PLEKHG7 | PLEKHH1 | PLEKHH2 | PLEKHH3 | PLEKHJ1 | PLEKHM1 | PLEKHM1P1 | PLEKHM2 | PLEKHM3 | PLEKHN1 | PLEKHO1 | PLEKHO2 | PLEKHS1 | PLET1 | Plexin | PLG | PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3 | PLPPR4 | PLPPR5 | PLPPR5-AS1 | PLRG1 | PLS1 | PLS3 | PLSCR1