Target Name: PLBD1
NCBI ID: G79887
Review Report on PLBD1 Target / Biomarker Content of Review Report on PLBD1 Target / Biomarker
PLBD1
Other Name(s): Phospholipase B-like 1 chain C | phospholipase B domain containing 1 | lamina ancestor homolog 1 | Phospholipase B-like 1 chain B | Phospholipase B domain containing 1 | phospholipase B domain-containing protein 1 | Phospholipase B-like 1 | Phospholipase B-like 1 chain A | PLB homolog 1 | PLBL1_HUMAN | putative phospholipase B-like 1 | Lamina ancestor homolog 1 | LAMA-like protein 1 | Phospholipase B domain-containing protein 1

PLBD1: A Potential Drug Target Or Biomarker

PLBD1 (Phospholipase B-like 1 chain C) is a protein that is expressed in various cell types, including neurons, muscle cells, and blood vessels. It is a member of the phospholipase B family, which is involved in the breaking down of phospholipid molecules.

PLBD1 has been identified as a potential drug target or biomarker for several diseases, including cardiovascular disease, neurodegenerative diseases, and cancer.

One of the reasons why PLBD1 is considered a potential drug target is its involvement in the regulation of cell signaling pathways. PLBD1 has been shown to play a role in the signaling pathway known as the phosphatidylinositol (PMA) signaling pathway. This pathway is involved in the regulation of various cellular processes, including cell signaling, cell division, and cell survival.

Research has also shown that PLBD1 is involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. This suggests that PLBD1 may be a useful target for treatments aimed at increasing blood flow to the brain, such as those used to treat neurodegenerative diseases.

Another potential use of PLBD1 as a drug target is its role in the regulation of inflammation. PLBD1 has been shown to play a role in the production of pro-inflammatory cytokines, which can contribute to the development and progression of inflammatory diseases.

In addition to its potential as a drug target, PLBD1 has also been identified as a potential biomarker for several diseases. For example, PLBD1 has been shown to be elevated in the blood of individuals with Alzheimer's disease, a neurodegenerative disease. This suggests that PLBD1 may be a useful biomarker for this disease, and could be used to identify individuals at risk for the disease before the development of symptoms.

PLBD1 has also been shown to be elevated in the blood of individuals with cancer, which suggests that it may be a useful biomarker for cancer. This could be useful for the development of targeted therapies aimed at treating cancer.

In conclusion, PLBD1 is a protein that is involved in the regulation of various cellular processes, including cell signaling, angiogenesis, and inflammation. As a result, it is a potential drug target or biomarker for several diseases, including cardiovascular disease, neurodegenerative diseases, and cancer. Further research is needed to fully understand the role of PLBD1 in these diseases and to develop effective treatments.

Protein Name: Phospholipase B Domain Containing 1

Functions: In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids

The "PLBD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLBD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PLBD1-AS1 | PLBD2 | PLCB1 | PLCB2 | PLCB3 | PLCB4 | PLCD1 | PLCD3 | PLCD4 | PLCE1 | PLCE1-AS2 | PLCG1 | PLCG1-AS1 | PLCG2 | PLCH1 | PLCH2 | PLCL1 | PLCL2 | PLCXD1 | PLCXD2 | PLCXD3 | PLCZ1 | PLD1 | PLD2 | PLD3 | PLD4 | PLD5 | PLD6 | PLEC | PLEK | PLEK2 | PLEKHA1 | PLEKHA2 | PLEKHA3 | PLEKHA4 | PLEKHA5 | PLEKHA6 | PLEKHA7 | PLEKHA8 | PLEKHA8P1 | PLEKHB1 | PLEKHB2 | PLEKHD1 | PLEKHF1 | PLEKHF2 | PLEKHG1 | PLEKHG2 | PLEKHG3 | PLEKHG4 | PLEKHG4B | PLEKHG5 | PLEKHG6 | PLEKHG7 | PLEKHH1 | PLEKHH2 | PLEKHH3 | PLEKHJ1 | PLEKHM1 | PLEKHM1P1 | PLEKHM2 | PLEKHM3 | PLEKHN1 | PLEKHO1 | PLEKHO2 | PLEKHS1 | PLET1 | Plexin | PLG | PLGLA | PLGLB1 | PLGLB2 | PLGRKT | PLIN1 | PLIN2 | PLIN3 | PLIN4 | PLIN5 | PLK1 | PLK2 | PLK3 | PLK4 | PLK5 | PLLP | PLN | PLOD1 | PLOD2 | PLOD3 | PLP1 | PLP2 | PLPBP | PLPP1 | PLPP2 | PLPP3 | PLPP4 | PLPP5 | PLPP6 | PLPP7 | PLPPR1 | PLPPR2 | PLPPR3