PRICKLE2: A Drug Target / Disease Biomarker (G166336)

Target Name: PRICKLE2

NCBI ID: G166336

PRICKLE2

PRICKLE2: A Drug Target / Disease Biomarker

PRICKLE2 is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and muscle. Its full name is PRickle2-containing gene 2, and it is also known as PDC1. PRICKLE2 is a member of the PIC gene family, which encodes a variety of cytoplasmic protein-coding genes.

PRICKLE2 is unique among its kind because of its structure and its expression patterns. It is a cytoplasmic protein that is expressed in a variety of tissues, but its levels vary depending on the tissue and the developmental stage of the organism. PRICKLE2 is also expressed in the brain, which suggests that it may be involved in the development and maintenance of neural tissue.

One of the key functions of PRICKLE2 is its role in cell signaling. It is a protein that is involved in the signaling pathway known as the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and it is a key factor in the development and maintenance of tissues throughout the body.

PRICKLE2 is also involved in the regulation of inflammation. It is a protein that is expressed in the immune system and is involved in the response to bacterial and viral infections. It is thought to help to regulate the recruitment of immune cells to the site of infection and to trigger the production of antibodies to fight off the infection.

In addition to its role in cell signaling and inflammation, PRICKLE2 is also involved in the regulation of the blood-brain barrier. The blood-brain barrier is a barrier that separates the brain from the bloodstream, and it helps to protect the brain from harmful substances that could cause injury or disease. PRICKLE2 is thought to be involved in the regulation of the blood-brain barrier, which may be important for the safe and effective exchange of nutrients and oxygen between the brain and the bloodstream.

Overall, PRICKLE2 is a protein that is involved in a variety of important cellular processes throughout the body. Its unique structure and its expression patterns make it an attractive target for research into a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of PRICKLE2 in these diseases and to develop effective treatments.

Protein Name: Prickle Planar Cell Polarity Protein 2

The "PRICKLE2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRICKLE2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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