TMEM181: A Potential Drug Target Or Biomarker (G57583)

Target Name: TMEM181

NCBI ID: G57583

TMEM181

TMEM181: A Potential Drug Target Or Biomarker

TMEM181 (KiAA1423) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the kilhong family, which is a family of transmembrane proteins that are involved in various cellular processes . TMEM181 is known for its role in the regulation of mitochondrial function and energy metabolism.

In recent years, TMEM181 has gained significant interest as a potential drug target or biomarker due to its unique structure and function. The protein is involved in the formation of the mitochondrial outer membrane, which is responsible for maintaining the structural integrity of the mitochondria and protecting them from various insults. TMEM181 is also involved in the regulation of mitochondrial fission and fusion, which are important processes for maintaining energy metabolism.

TMEM181 has been shown to play a role in a variety of diseases, including neurodegenerative disorders, cardiovascular disease, and cancer. For example, studies have shown that TMEM181 is overexpressed in the brains of patients with Alzheimer's disease, which is a neurodegenerative disorder that is Characterized by the progressive loss of brain cells. Additionally, TMEM181 has been shown to be involved in the regulation of the blood-brain barrier, which is a barrier that separates the brain from the blood and is involved in the delivery of drugs and other substances to the brain.

In addition to its potential clinical applications, TMEM181 has also generated a lot of interest as a potential biomarker. The protein is expressed in a variety of tissues and can be used as a protein biomarker for various diseases, including neurodegenerative disorders, cardiovascular disease, and cancer. For example, studies have shown that TMEM181 can be used as a biomarker for Alzheimer's disease, with researchers using it to track the progression of the disease in models mouse of the condition.

TMEM181 is also a potential drug target due to its unique structure and function. The protein is involved in the regulation of mitochondrial function and energy metabolism, which are critical processes for maintaining the health and function of the brain. By targeting TMEM181, researchers may be able to develop new treatments for a variety of diseases, including neurodegenerative disorders, cardiovascular disease, and cancer.

In conclusion, TMEM181 is a protein that is expressed in various tissues of the body and is involved in the regulation of mitochondrial function and energy metabolism. Its unique structure and function make it an attractive potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of TMEM181 in various biological processes and to develop new treatments based on its unique properties.

Protein Name: Transmembrane Protein 181

Functions: Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication

The "TMEM181 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM181 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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