Target Name: TMEM182
NCBI ID: G130827
Review Report on TMEM182 Target / Biomarker Content of Review Report on TMEM182 Target / Biomarker
TMEM182
Other Name(s): TM182_HUMAN | Transmembrane protein 182, transcript variant 1 | transmembrane protein 182 | TMEM182 variant 1 | Transmembrane protein 182 | Transmembrane protein 182 isoform a precursor (isoform a)

TMEM182: A Protein Involved in Cell Signaling Pathways and Cell Cycle Regulation

TMEM182 (TM182_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is a member of the transmembrane protein family, which means that it spans the cell membrane and functions as a protein that interacts with other proteins and molecules on both sides of the membrane.

TMEM182 has been identified as a potential drug target and has been shown to play a role in a variety of biological processes. One of the key functions of TMEM182 is its role in the regulation of cell signaling pathways, which are the processes by which cells communicate with one another to carry out various tasks.

TMEM182 has been shown to interact with a variety of protein molecules, including the protein tyrosine kinase (TK) and the protein serine/threonine kinase (STK). These interactions are important for the regulation of cell signaling pathways and are implicated in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In addition to its role in cell signaling pathways, TMEM182 has also been shown to play a role in the regulation of cellular processes that are important for the structure and function of the cell. For example, TMEM182 has been shown to be involved in the regulation of the cytoskeleton, which is the structure that gives cells their shape and supports their internal organs.

TMEM182 has also been shown to be involved in the regulation of the cell cycle, which is the process by which cells grow, divide, and replicate their genetic material. This is important for the development and progression of cancer, as well as the normal growth and development of tissues.

In conclusion, TMEM182 is a protein that has been identified as a potential drug target due to its role in the regulation of cell signaling pathways, cellular processes that are important for the structure and function of the cell, and the regulation of the cell cycle. Further research is needed to fully understand the role of TMEM182 in these biological processes and to develop effective treatments for diseases associated with its dysfunction.

Protein Name: Transmembrane Protein 182

Functions: Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (By similarity). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (By similarity)

The "TMEM182 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM182 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TMEM183A | TMEM183BP | TMEM184A | TMEM184B | TMEM184C | TMEM185A | TMEM185B | TMEM186 | TMEM187 | TMEM19 | TMEM190 | TMEM191A | TMEM191B | TMEM191C | TMEM192 | TMEM196 | TMEM198 | TMEM198B | TMEM199 | TMEM200A | TMEM200B | TMEM200C | TMEM201 | TMEM202 | TMEM203 | TMEM204 | TMEM205 | TMEM207 | TMEM208 | TMEM209 | TMEM210 | TMEM212 | TMEM213 | TMEM214 | TMEM215 | TMEM216 | TMEM217 | TMEM218 | TMEM219 | TMEM220 | TMEM220-AS1 | TMEM221 | TMEM222 | TMEM223 | TMEM225 | TMEM225B | TMEM229A | TMEM229B | TMEM230 | TMEM231 | TMEM232 | TMEM233 | TMEM234 | TMEM235 | TMEM236 | TMEM237 | TMEM238 | TMEM238L | TMEM239 | TMEM240 | TMEM241 | TMEM242 | TMEM243 | TMEM244 | TMEM245 | TMEM246-AS1 | TMEM247 | TMEM248 | TMEM249 | TMEM25 | TMEM250 | TMEM252 | TMEM253 | TMEM254 | TMEM254-AS1 | TMEM255A | TMEM255B | TMEM256 | TMEM256-PLSCR3 | TMEM257 | TMEM258 | TMEM259 | TMEM26 | TMEM260 | TMEM263 | TMEM265 | TMEM266 | TMEM267 | TMEM268 | TMEM270 | TMEM271 | TMEM272 | TMEM273 | TMEM30A | TMEM30A-DT | TMEM30B | TMEM30CP | TMEM31 | TMEM33 | TMEM35A