SH2D3C: A Potential Drug Target and Biomarker (G10044)

Target Name: SH2D3C

NCBI ID: G10044

SH2D3C

SH2D3C: A Potential Drug Target and Biomarker

SH2D3C is a protein that is expressed in various tissues, including the brain, heart, and kidneys. Its full name is SH2D3C gene 3c, and it is a member of the T-cell receptor (TCR) family. SH2D3C is highly conserved across different species, and it has been implicated in various physiological processes in both humans and animals.

One of the most promising aspects of SH2D3C is its potential as a drug target. SH2D3C has been shown to play a critical role in the regulation of immune responses, and it has been identified as a potential target for small molecule inhibitors. Several studies have shown that SH2D3C is involved in the development of various diseases, including cancer, autoimmune diseases, and neurodegenerative disorders.

In addition to its potential as a drug target, SH2D3C has also been identified as a biomarker for several diseases. Its expression has been shown to be elevated in various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. This suggests that SH2D3C may be a useful biomarker for these diseases, and that it may be able to serve as a guide for the development of new therapies.

The discovery and characterization of SH2D3C as a potential drug target and biomarker has important implications for the development of new therapies for various diseases. SH2D3C has been shown to be involved in the regulation of immune responses, and it has been identified as a potential target for small molecule inhibitors. Further research is needed to fully understand the role of SH2D3C in these processes and to develop new treatments based on this understanding.

Protein Name: SH2 Domain Containing 3C

Functions: Acts as an adapter protein that mediates cell signaling pathways involved in cellular functions such as cell adhesion and migration, tissue organization, and the regulation of the immune response (PubMed:12432078, PubMed:20881139). Plays a role in integrin-mediated cell adhesion through BCAR1-CRK-RAPGEF1 signaling and activation of the small GTPase RAP1 (PubMed:12432078). Promotes cell migration and invasion through the extracellular matrix (PubMed:20881139). Required for marginal zone B-cell development and thymus-independent type 2 immune responses (By similarity). Mediates migration and adhesion of B cells in the splenic marginal zone via promoting hyperphosphorylation of NEDD9/CASL (By similarity). Plays a role in CXCL13-induced chemotaxis of B-cells (By similarity). Plays a role in the migration of olfactory sensory neurons (OSNs) into the forebrain and the innervation of the olfactory bulb by the OSN axons during development (By similarity). Required for the efficient tyrosine phosphorylation of BCAR1 in OSN axons (By similarity)

The "SH2D3C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SH2D3C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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