NOM1: A Potential Drug Target and Biomarker for Nucleolar MIF4G Domain-Containing Proteins

Target Name: NOM1

NCBI ID: G64434

NOM1

NOM1: A Potential Drug Target and Biomarker for Nucleolar MIF4G Domain-Containing Proteins

Introduction

Nucleolar MIF4G domain-containing proteins (NOMPs) are a family of proteins that play crucial roles in the regulation of nuclear structure and function. NOMPs are involved in various cellular processes, including DNA replication, gene expression, and chromatin remodeling. The NOM1 protein is one of the NOMPs that has been well-studied, and its function in various cellular processes has been extensively investigated.

In this article, we will discuss the NOM1 protein, its functions, potential drug targets, and potential use as a biomarker.

Function and Localization

NOM1 is a 21-kDa protein that is localized to the nucleolar matrix. It is composed of a unique N-terminal region, a middle domain, and a C-terminal region. The N-terminal region contains a nucleolar localization signal (NLS) , which is responsible for the protein's nuclear localization. The middle domain contains the NOM1-specific domain, which is responsible for various cellular processes, including the regulation of nuclear structure and function. The C-terminal region contains a conserved tail region that is involved in protein-protein interactions and may contribute to the protein's stability.

NOM1 is involved in various cellular processes, including the regulation of nuclear structure and function, DNA replication, gene expression, and chromatin remodeling. One of the well-studied functions of NOM1 is its role in the regulation of the size and composition of the nucleolar matrix. NOM1 has been shown to play a crucial role in the regulation of the size of the nucleolar matrix, as well as the composition of the matrix, by interacting with the protein components that are involved in these processes.

Potential Drug Targets

NOM1 is a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. One of the reasons for its potential as a drug target is its unique structure, as well as its involvement in various cellular processes that are associated with the development and progression of these diseases.

NOM1 has been shown to interact with various drugs, including inhibitors of the PI3K/Akt signaling pathway, which is involved in the regulation of cellular processes that are associated with the development and progression of cancer. In addition, NOM1 has been shown to interact with drugs that are used to treat neurodegenerative diseases, such as small interneuron-specific neurotrophic factor (SINN) RNA inhibitors.

Potential Biomarkers

NOM1 has the potential to serve as a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. One of the reasons for its potential as a biomarker is its involvement in various cellular processes that are associated with the development and progression of these diseases.

NOM1 has been shown to be involved in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation. In addition, NOM1 has been shown to be involved in the regulation of the expression of various genes, including genes that are involved in the development and progression of cancer.

Conclusion

In conclusion, NOM1 is a unique and well-studied protein that is involved in various cellular processes that are associated with the development and progression of cancer, neurodegenerative diseases, and autoimmune diseases. Its unique structure and various functions make it a potential drug target and biomarker. Further research is needed to fully understand the role of NOM1 in these processes and its potential as a drug target and biomarker.

Protein Name: Nucleolar Protein With MIF4G Domain 1

Functions: Plays a role in targeting PPP1CA to the nucleolus

The "NOM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NOM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets