Target Name: STIL
NCBI ID: G6491
Review Report on STIL Target / Biomarker Content of Review Report on STIL Target / Biomarker
STIL
Other Name(s): DKFZp686O09161 | SCL-interrupting locus protein (isoform 2) | OTTHUMP00000009566 | SIL | STIL centriolar assembly protein | TAL1 (SCL) interrupting locus | SCL/TAL1 interrupting locus | MCPH7 | STIL centriolar assembly protein, transcript variant 2 | SCL interrupting locus | STIL variant 2 | STIL variant 1 | SCL-interrupting locus protein (isoform 1) | TAL-1-interrupting locus protein | SCL-interrupting locus protein | STIL_HUMAN | STIL centriolar assembly protein, transcript variant 1

STIL: A Promising Drug Target and Biomarker

STIL (DKFZp686O09161) is a drug target and a biomarker that is being studied for its potential in treating various diseases, including cancer. It is a small molecule that is derived from a natural compound found in the soil, and it has been shown to have anti-inflammatory and anti-tumor effects.

STIL is currently being investigated for its potential as a drug target in a number of diseases, including cancer. For example, studies have shown that STIL can inhibit the growth of cancer cells in cell cultures, and it has been shown to have potential in treating various types of cancer, including breast, lung, and ovarian cancer.

In addition to its potential as a cancer drug, STIL has also been shown to have potential as a biomarker for the disease. It can increase tumor markers, such as CA19-9, in the serum of some tumor patients, thereby helping doctors diagnose the disease. Monitor and treat.

STIL is also a good candidate as a drug target because it is relatively simple to synthesize and has a low potential for adverse effects. This makes it an attractive candidate for use in humans as a drug.

In conclusion, STIL is a promising drug target and biomarker that has the potential to treat a variety of diseases, including cancer. Further research is needed to fully understand its potential and to develop safe and effective treatments.

Protein Name: STIL Centriolar Assembly Protein

Functions: Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Plays a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1 (PubMed:16024801, PubMed:9372240). Plays an important role in the regulation of centriole duplication. Required for the onset of procentriole formation and proper mitotic progression. During procentriole formation, is essential for the correct loading of SASS6 and CENPJ to the base of the procentriole to initiate procentriole assembly (PubMed:22020124)

The "STIL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about STIL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

STIM1 | STIM2 | STIMATE | STIN2-VNTR | STING1 | STIP1 | STK10 | STK11 | STK11IP | STK16 | STK17A | STK17B | STK19 | STK24 | STK25 | STK26 | STK3 | STK31 | STK32A | STK32A-AS1 | STK32B | STK32C | STK33 | STK35 | STK36 | STK38 | STK38L | STK39 | STK4 | STK4-DT | STK40 | STKLD1 | STMN1 | STMN2 | STMN3 | STMN4 | STMND1 | STMP1 | STN1 | STOM | STOML1 | STOML2 | STOML3 | STON1 | STON1-GTF2A1L | STON2 | Store-operating calcium channel channels | STOX1 | STOX2 | STPG1 | STPG2 | STPG3 | STPG3-AS1 | STPG4 | STRA6 | STRA6LP | STRA8 | STRADA | STRADB | STRAP | STRBP | STRC | STRCP1 | STRIP1 | STRIP2 | STRIT1 | STRN | STRN3 | STRN4 | STS | STT3A | STT3A-AS1 | STT3B | STUB1 | STUM | STX10 | STX11 | STX12 | STX16 | STX16-NPEPL1 | STX17 | STX17-DT | STX18 | STX18-AS1 | STX18-IT1 | STX19 | STX1A | STX1B | STX2 | STX3 | STX4 | STX5 | STX5-DT | STX6 | STX7 | STX8 | STXBP1 | STXBP2 | STXBP3 | STXBP4