Target Name: ENOX2
NCBI ID: G10495
Review Report on ENOX2 Target / Biomarker Content of Review Report on ENOX2 Target / Biomarker
ENOX2
Other Name(s): Protein disulfide-thiol oxidoreductase | ENOX2 variant 1 | COVA1 | OTTHUMP00000024022 | tumor-associated NADH oxidase | Ecto-NOX disulfide-thiol exchanger 2, transcript variant 1 | Hydroquinone [NADH] oxidase | OTTHUMP00000024021 | Tumor-associated hydroquinone oxidase | Cytosolic ovarian carcinoma antigen 1 | ecto-NOX disulfide-thiol exchanger 2 | ENOX2_HUMAN | APK1 antigen | cytosolic ovarian carcinoma antigen 1 | tumor-associated hydroquinone oxidase | tNOX | Ecto-NOX disulfide-thiol exchanger 2 isoform a | APK1 | Ecto-NOX disulfide-thiol exchanger 2 | ecto-NADPH oxidase disulfide-thiol exchanger 2

ENOX2: A Protein Disulfide-Thiol Oxidoreductase and a Potential Drug Target

Protein disulfide-thiol oxidoreductase (ENOX2) is a gene that encodes a protein involved in cell signaling pathways, specifically the NF-kappa pathway. ENOX2 plays a crucial role in regulating the level of reactive oxygen species (ROS) in the cell, which can cause damage to cellular components and contribute to various diseases, including cancer. ROS are generated by cellular processes that require energy, such as metabolism, and can be generated by various cellular pathways, including the citric acid cycle and the electron transport chain. ENOX2 is a key enzyme that converts the reactive oxygen species generated by these pathways to less reactive forms, thereby preventing damage to cellular components.

ENOX2 is a protein that can be found in various cell types, including epithelial, muscle, and neural cells. It is expressed in high levels in the liver, heart, and pancreas, and its expression is also upregulated in response to various cellular stressors, such as UV radiation, chemical stress, and oxidative stress. ENOX2 is involved in the detoxification of ROS, which are generated by cellular stressors, and it has been shown to have a wide range of physiological functions, including the regulation of cell growth, differentiation, and survival.

ENOX2 as a Potential Drug Target

ENOX2 has been identified as a potential drug target due to its involvement in various cellular signaling pathways and its involvement in the detoxification of ROS. Many diseases, including cancer, are caused by the accumulation of ROS, which can cause damage to cellular components and contribute to the development of various diseases. ENOX2 has been shown to have a role in the regulation of ROS levels and has been shown to interact with various signaling pathways, including the NF-kappa pathway. Therefore, ENOX2 may be a useful drug target for the treatment of diseases caused by the accumulation of ROS.

One of the potential benefits of targeting ENOX2 is its potential to inhibit the production of ROS. ENOX2 is involved in the detoxification of ROS, which means that it can be used to reduce the levels of ROS in the body. This can be done by inhibiting the activity of ENOX2, which would result in the accumulation of ROS in the body. This can be a useful strategy for the treatment of diseases caused by the accumulation of ROS, such as cancer.

Another potential benefit of targeting ENOX2 is its potential to enhance the clearance of ROS. ENOX2 has been shown to have a role in the detoxification of ROS, which means that it can be used to enhance the clearance of ROS from the body. This can be done by increasing the activity of ENOX2, which would result in the rapid clearance of ROS from the body. This can be a useful strategy for the treatment of diseases caused by the accumulation of ROS, such as cancer.

ENOX2 as a Potential biomarker

ENOX2 has also been identified as a potential biomarker for the diagnosis and monitoring of various diseases. ENOX2 is involved in the detoxification of ROS, which means that it can be used to measure the levels of ROS in the body. This can be done by measuring the levels of ENOX2 in the body, which can indicate the level of ROS generated by cellular stressors. This can be a useful strategy for the diagnosis and monitoring of diseases caused by the accumulation of ROS, such as cancer.

ENOX2 has also been shown to have a role in the regulation of cellular stressors, which can

Protein Name: Ecto-NOX Disulfide-thiol Exchanger 2

Functions: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock

The "ENOX2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENOX2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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