ENO2: A Potential Drug Target for Fatty Acid Metabolism (G2026)

Target Name: ENO2

NCBI ID: G2026

ENO2

ENO2: A Potential Drug Target for Fatty Acid Metabolism

ENO2 (Gamma-enolase), a enzyme found in various organisms, plays a crucial role in the metabolism of fatty acids. It is a key player in the citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, which is a central metabolic pathway that generates energy in the form of ATP. ENO2 is critical for the rate at which fatty acids are broken down and converted into energy.

ENO2 has been identified as a potential drug target or biomarker for several reasons. Firstly, ENO2 has been shown to be involved in the development and progression of various diseases, including cancer, obesity, and neurodegenerative diseases. Secondly, ENO2 has been shown to have therapeutic potential in treating certain diseases, such as cancer, by inhibiting the activity of ENO2-dependent enzymes. Finally, ENO2 has been shown to be a good predictor of therapeutic response to ENO2 inhibitors, which suggests that it may be a useful biomarker for tracking the effectiveness of such treatments.

One of the main functions of ENO2 is its role in the citric acid cycle. In this process, ENO2 is involved in the breakdown of fatty acids, which are then converted into energy in the form of ATP. This process occurs in two stages. The first stage is the citric acid cycle, also known as the Krebs cycle or TCA cycle. In this stage, ENO2 is involved in the breakdown of fatty acids from the food we eat into carbon dioxide, water, and ATP.

The citric acid cycle is a crucial step in the metabolism of fatty acids and is critical for the production of energy. It is also involved in the production of many other molecules, including amino acids, nucleotides, and lipids. The citric acid cycle is divided into three stages: the electron transport chain, the citric acid cycle, and the electron transport chain.

The electron transport chain is the first stage in the citric acid cycle. In this stage, ENO2 is involved in the transfer of electrons from the electron acceptor to the electron donor. This process is crucial for the production of ATP, which is the energy currency of the cell. The electron transport chain is also known as the NADH-dependent electron transport chain.

The second stage is the citric acid cycle. In this stage, ENO2 is involved in the breakdown of fatty acids from the food we eat into carbon dioxide, water, and ATP. This process occurs through a series of complex chemical reactions, including the citric acid cycle, the 2-oxoglutarate shunt, and the electron transport chain.

The electron transport chain is the final stage in the citric acid cycle. In this stage, ENO2 is involved in the transfer of electrons from the electron acceptor to the electron donor. This process is crucial for the production of ATP, which is the energy currency of the cell. The electron transport chain is also known as the NADH-dependent electron transport chain.

ENO2 is a key player in the electron transport chain and is involved in the production of ATP. It is also involved in the breakdown of fatty acids from the food we eat into carbon dioxide, water, and ATP. This process occurs through a series of complex chemical reactions, including the citric acid cycle, the 2-oxoglutarate shunt, and the electron transport chain.

ENO2 has been shown to be involved in the development and progression of various diseases, including cancer, obesity, and neurodegenerative diseases. For example, studies have shown that ENO2 is involved in the progression of cancer by promoting the growth and survival of cancer cells. It has also been shown to be involved in the development of obesity by

Protein Name: Enolase 2

Functions: Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity)

The "ENO2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENO2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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