TMEM105: A promising drug target and biomarker for the treatment of various diseases

Target Name: TMEM105

NCBI ID: G284186

TMEM105

Other Name(s): TMEM105 long non-coding RNA | TM105_HUMAN | Transmembrane protein 105

TMEM105: A promising drug target and biomarker for the treatment of various diseases

TMEM105 is a long non-coding RNA (lncRNA) that has been identified as a potential drug target and biomarker for the treatment of various diseases. It is a non-coding RNA molecule that is approximately 200 nucleotides long and is expressed in various tissues and cells of the body. TMEM105 is a key player in the regulation of gene expression and has been shown to play a crucial role in the development and progression of various diseases.

The discovery and characterization of TMEM105

TMEM105 was first identified using transcriptomics techniques. The RNA sequencing (RNA-seq) data from a variety of organisms, including human, revealed that TMEM105 was highly expressed in various tissues and cells of the body. The expression of TMEM105 was also highly associated with the expression of genes involved in cell signaling pathways, such as TGF-β signaling pathway, GATA3 signaling pathway, and NF-kappa-B signaling pathway.

The functions of TMEM105

TMEM105 is involved in the regulation of gene expression and has been shown to play a crucial role in the development and progression of various diseases. One of the functions of TMEM105 is to act as a negative regulator of the TGF-β signaling pathway. TGF-β is a well-known transcription factor that regulates cell signaling pathways, including cell proliferation, differentiation, and survival. TMEM105 has been shown to physically interact with the TGF-β receptor and prevent it from activating target genes.

Another function of TMEM105 is to act as a negative regulator of the GATA3 signaling pathway. GATA3 is a non-coding RNA-binding protein that regulates gene expression by binding to specific DNA sequences. TMEM105 has been shown to physically interact with the GATA3 protein and prevent it from activating target genes.

In addition to its functions as a negative regulator of TGF-β and GATA3 signaling pathways, TMEM105 has also been shown to play a role in the regulation of cell adhesion. Adhesion is a critical process that allows cells to stick together and form tissues. TMEM105 has been shown to be involved in the regulation of cell adhesion and has been shown to play a positive role in the development of cancer.

The potential uses of TMEM105 as a drug target

The potential uses of TMEM105 as a drug target are vast. TMEM105 has been shown to play a role in the regulation of cell signaling pathways, including TGF-β and GATA3 signaling pathways. As a result, TMEM105 may be a useful target for the treatment of diseases that are caused by the regulation of these signaling pathways, such as cancer, neurodegenerative diseases, and autoimmune diseases.

In addition to its potential as a drug target, TMEM105 may also be a useful biomarker for the diagnosis and monitoring of various diseases. The expression of TMEM105 is highly associated with the expression of genes involved in cell signaling pathways, such as TGF-β and GATA3 signaling pathways. As a result, the expression of TMEM105 may be a useful indicator of the level of cell signaling activity and the overall health of the body.

Conclusion

TMEM105 is a promising drug target and biomarker for the treatment of various diseases. Its functions as a negative regulator of TGF-β and GATA3 signaling pathways suggest that it may be an effective target for the treatment of diseases caused by the regulation of these signaling pathways, such as cancer, neurodegenerative diseases, and autoimmune diseases. The potential use of TMEM105 as a biomarker for the diagnosis and monitoring of various diseases is also a promising direction for future research. Further studies are needed to fully understand the role of TMEM105 in the regulation of cell signaling pathways and its potential as a drug

Protein Name: TMEM105 Long Non-coding RNA

The "TMEM105 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM105 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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