Target Name: KXD1
NCBI ID: G79036
Review Report on KXD1 Target / Biomarker Content of Review Report on KXD1 Target / Biomarker
KXD1
Other Name(s): KxDL motif containing 1 | KxDL motif-containing protein 1 | MST096 | BORCS4 | KXD1 variant 1 | KxDL motif containing 1, transcript variant 1 | C19orf50 | KXDL1_HUMAN | C10orf50 | KXDL | BLOC-1 related complex subunit 4 | MSTP096 | UPF0459 protein C19orf50

KXD1: A Potential Drug Target for Cell Adhesion, Signaling and Inflammation

KXD1, also known as KxDL motif containing 1, is a protein that has been identified as a potential drug target or biomarker. The protein is found in various tissues throughout the body and is involved in a number of cellular processes.

The KxDL motif is a conserved region of DNA that is found in multiple organisms, including humans. It is characterized by the presence of a specific DNA binding motif, known as the KxDL motif, which is composed of the amino acids K, X, D, and L. The KxDL motif is thought to play a role in the regulation of various cellular processes, including cell growth, differentiation, and inflammation.

One of the reasons why KXD1 is considered a potential drug target is its involvement in the regulation of cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs. In various diseases, such as cancer, abnormal cell adhesion can contribute to the development and progression of the disease.

KXD1 has been shown to play a role in the regulation of cell adhesion by affecting the interactions between cells and the extracellular matrix (ECM). Several studies have shown that KXD1 promotes the stickiness of cancer cells to ECM, which allows them to form tumors and spread throughout the body.

Another potential drug target for KXD1 is its role in cell signaling. KXD1 has been shown to play a role in the regulation of various signaling pathways, including T cell signaling, which is important for cell growth, survival, and differentiation.

KXD1 has also been shown to be involved in the regulation of inflammation. Inflammation is a natural response of the immune system to injury or infection, but chronic inflammation can contribute to a number of diseases, including heart disease, diabetes, and cancer.

Several studies have shown that KXD1 plays a role in the regulation of inflammation by affecting the production and function of immune cells. In addition, KXD1 has been shown to influence the expression of genes involved in inflammation, including the production of pro-inflammatory cytokines.

In conclusion, the KxDL motif containing 1 is a protein that has been identified as a potential drug target or biomarker. Its involvement in the regulation of cell adhesion, signaling, and inflammation makes it a promising target for future research and development. Further studies are needed to fully understand the role of KXD1 in these processes and to develop effective therapies for the treatment of diseases associated with its dysfunction.

Protein Name: KxDL Motif Containing 1

Functions: As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity)

The "KXD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KXD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KY | KYAT1 | KYAT3 | KYNU | L-Type calcium channel | L-type voltage-dependent calcium channel complex | L1CAM | L1CAM-AS1 | L1TD1 | L2HGDH | L3HYPDH | L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 | L3MBTL4-AS1 | LACAT1 | LACC1 | LACRT | Lactate Dehydrogenase (LDH) | LACTB | LACTB2 | LACTB2-AS1 | LACTBL1 | LAD1 | LAG3 | LAGE3 | LAIR1 | LAIR2 | LALBA | LAMA1 | LAMA2 | LAMA3 | LAMA4 | LAMA5 | LAMB1 | LAMB2 | LAMB2P1 | LAMB3 | LAMB4 | LAMC1 | LAMC1-AS1 | LAMC2 | LAMC3 | Laminin-5 | Laminins | LAMP1 | LAMP2 | LAMP3 | LAMP5 | LAMP5-AS1 | LAMTOR1 | LAMTOR2 | LAMTOR3 | LAMTOR3P1 | LAMTOR4 | LAMTOR5 | LAMTOR5-AS1 | LanC-like proteins | LANCL1 | LANCL1-AS1 | LANCL2 | LANCL3 | LAP3 | LAP3P2 | LAPTM4A | LAPTM4B | LAPTM4BP2 | LAPTM5 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) | LARGE-AS1 | LARGE1 | LARGE2 | LARP1 | LARP1B | LARP4 | LARP4B | LARP4P | LARP6 | LARP7 | LARS1 | LARS2 | LAS1L | LASP1 | LAT | LAT2 | LATS1 | LATS2 | LAX1 | LAYN | LBH | LBHD1 | LBP | LBR | LBX1 | LBX1-AS1 | LBX2 | LBX2-AS1 | LCA5 | LCA5L