Target Name: L1CAM
NCBI ID: G3897
Review Report on L1CAM Target / Biomarker Content of Review Report on L1CAM Target / Biomarker
L1CAM
Other Name(s): CD171 | L1CAM C-terminal fragment | L1 cell adhesion molecule, transcript variant 3 | MASA | L1CAM (CTF2) | OTTHUMP00000025992 | L1 cell adhesion molecule, transcript variant 4 | OTTHUMP00000025993 | L1 cell adhesion molecule (L1CAM) | N-CAM-L1 | HSAS1 | L1CAM variant 4 | NCAM-L1 | HSAS | S10 | L1CAM_HUMAN | L1CAM (CTF2)_(HUMAN) | L1 cell adhesion molecule | L1CAM intracellular domain | OTTHUMP00000063091 | Neural cell adhesion molecule L1 (isoform 3) | L1 cell adhesion molecule, transcript variant 1 | antigen identified by monoclonal antibody R1 | L1CAM variant 1 | MIC5 | N-CAML1 | SPG1 | CAML1 | Neural cell adhesion molecule L1 | L1CAM (CTF1) | Neural cell adhesion molecule L1 (isoform 1) | Antigen identified by monoclonal antibody R1 | L1CAM variant 3 | L1CAM (CTF1)_(HUMAN)

L1CAM: Potential Drug Target for Immune and Cancer-Related Processes

L1CAM, also known as CD171, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the Camel family of transmembrane proteins, which are characterized by the presence of a cytoplasmic tail and a transmembrane domain.

One of the most interesting aspects of L1CAM is its role in the regulation of inflammation. L1CAM has been shown to play a key role in the recruitment of immune cells to sites of infection or injury. This is accomplished through its ability to interact with several different types of immune cells, including T cells, which are known for their ability to recognize and respond to antigens presented by invading pathogens.

In addition to its role in immune regulation, L1CAM has also been shown to be involved in the regulation of cell survival and the development of cancer. Studies have suggested that L1CAM may be a potential drug target for the treatment of various types of cancer, due to its ability to promote the growth and survival of cancer cells.

The precise mechanism by which L1CAM promotes cancer growth is not well understood, but it is thought to involve several different processes. For example, L1CAM has been shown to play a role in the regulation of cell apoptosis, which is the process by which cells decide when to die and are programmed to do so.

In addition to its role in cancer promotion, L1CAM has also been shown to be involved in the regulation of cell signaling pathways that are important for the development and maintenance of tissues. For example, L1CAM has been shown to play a role in the regulation of the Wnt signaling pathway, which is important for the development and maintenance of tissues during embryonic development.

The potential clinical applications of L1CAM are vast, as it has been shown to play a key role in the regulation of both immune and cancer-related processes. As such, L1CAM is a potential drug target for the treatment of a wide range of diseases, including cancer, autoimmune disorders, and injuries.

In conclusion, L1CAM is a protein that has been shown to play a key role in the regulation of various processes in the body, including immune and cancer-related processes. Its potential clinical applications are vast, and it is a potential drug target for the treatment of a wide range of diseases. Further research is needed to fully understand the mechanisms by which L1CAM functions and to develop effective treatments for the various conditions that it is involved in.

Protein Name: L1 Cell Adhesion Molecule

Functions: Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity

The "L1CAM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about L1CAM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

L1CAM-AS1 | L1TD1 | L2HGDH | L3HYPDH | L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 | L3MBTL4-AS1 | LACAT1 | LACC1 | LACRT | Lactate Dehydrogenase (LDH) | LACTB | LACTB2 | LACTB2-AS1 | LACTBL1 | LAD1 | LAG3 | LAGE3 | LAIR1 | LAIR2 | LALBA | LAMA1 | LAMA2 | LAMA3 | LAMA4 | LAMA5 | LAMB1 | LAMB2 | LAMB2P1 | LAMB3 | LAMB4 | LAMC1 | LAMC1-AS1 | LAMC2 | LAMC3 | Laminin-5 | Laminins | LAMP1 | LAMP2 | LAMP3 | LAMP5 | LAMP5-AS1 | LAMTOR1 | LAMTOR2 | LAMTOR3 | LAMTOR3P1 | LAMTOR4 | LAMTOR5 | LAMTOR5-AS1 | LanC-like proteins | LANCL1 | LANCL1-AS1 | LANCL2 | LANCL3 | LAP3 | LAP3P2 | LAPTM4A | LAPTM4B | LAPTM4BP2 | LAPTM5 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) | LARGE-AS1 | LARGE1 | LARGE2 | LARP1 | LARP1B | LARP4 | LARP4B | LARP4P | LARP6 | LARP7 | LARS1 | LARS2 | LAS1L | LASP1 | LAT | LAT2 | LATS1 | LATS2 | LAX1 | LAYN | LBH | LBHD1 | LBP | LBR | LBX1 | LBX1-AS1 | LBX2 | LBX2-AS1 | LCA5 | LCA5L | LCAL1 | LCAT | LCDR | LCE1A | LCE1B | LCE1C | LCE1D