KRTAP9-9: A Potential Drug Target and Biomarker (G81870)

Target Name: KRTAP9-9

NCBI ID: G81870

KRTAP9-9

KRTAP9-9: A Potential Drug Target and Biomarker

Keratin-associated protein 9-5 (KRTAP9-9) is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to investigate.

The protein KRTAP9-9 is a member of the keratin family, which is known for their role in the development and maintenance of hair and nails. KRTAP9-9 is expressed in a variety of tissues, including skin, scalp, and hair, and has been shown to play a role in regulating cell growth and differentiation.

One of the key features of KRTAP9-9 is its ability to interact with various signaling pathways. It has been shown to play a role in the JAK/STAT signaling pathway, which is involved in the regulation of cell growth and survival. Additionally, KRTAP9-9 has been shown to interact with the TGF-β pathway, which is involved in the regulation of cell growth and differentiation.

These interactions between KRTAP9-9 and signaling pathways have led to its potential as a drug target. By targeting KRTAP9-9 with small molecules or antibodies, researchers may be able to disrupt its activity and reduce the growth or progression of cancer cells.

In addition to its potential as a drug target, KRTAP9-9 has also been shown to be a potential biomarker for various diseases. Its expression has been shown to be elevated in a variety of cancer types, including breast, ovarian, and prostate cancer. Additionally, KRTAP9-9 has been shown to be associated with poor prognosis in cancer patients.

These findings make KRTAP9-9 an attractive candidate for further research as a potential drug target and biomarker. By investigating its effects on cancer cell growth and behavior, researchers may be able to develop new treatments for a variety of diseases.

Protein Name: Keratin Associated Protein 9-9

Functions: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins

The "KRTAP9-9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRTAP9-9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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