USP9Y: A Key Enzyme in The Immune System (G8287)

Target Name: USP9Y

NCBI ID: G8287

USP9Y

USP9Y: A Key Enzyme in The Immune System

USP9Y, also known as ubiquitin-specific processing protease FAF-Y, is a protein that plays a crucial role in the body's immune system and helps to remove damaged or unnecessary proteins from the cells. It is a key enzyme in the ubiquitin system, which is a network of proteins that work together to break down and remove damaged or unnecessary proteins.

USP9Y is a 10-kDa protein that is expressed in a variety of tissues and cells in the body, including the liver, spleen, and muscle. It is highly conserved, with similar sequences found in a variety of species, including humans, mouse, and yeast.

One of the key functions of USP9Y is its role in the ubiquitin system. ubiquitin is a small protein that is highly involved in the immune response and helps to identify and tag proteins for destruction by the body's immune cells. USP9Y is a key enzyme that helps to break down and remove damaged or unnecessary ubiquitin proteins, which is critical for maintaining the health and function of the immune system.

In addition to its role in the ubiquitin system, USP9Y is also involved in the regulation of protein synthesis and degradation. It has been shown to play a role in the translation of DNA into protein and in the degradation of damaged proteins.

USP9Y is also a potential drug target and may be a biomarker for a variety of diseases. For example, USP9Y has been shown to be involved in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the potential reasons for USP9Y's involvement in these diseases is its role in the ubiquitin system. Many diseases are characterized by the accumulation of damaged or unnecessary proteins, which can contribute to the development and progression of these diseases. By removing these proteins, USP9Y may be able to help prevent the build-up of harmful substances in the body that can lead to the development of disease.

Another potential reason for USP9Y's involvement in disease is its role in the regulation of protein synthesis and degradation. Many diseases are characterized by the regulation of protein synthesis and degradation, which can be disrupted by the build-up of damaged or unnecessary proteins. By regulating protein synthesis and degradation, USP9Y may be able to help prevent the build-up of harmful substances in the body that can contribute to the development and progression of disease.

In conclusion, USP9Y is a protein that plays a crucial role in the immune system and helps to remove damaged or unnecessary proteins from the cells. It is a key enzyme in the ubiquitin system and is highly conserved across different species. USP9Y may be a potential drug target and may be a biomarker for a variety of diseases. Further research is needed to fully understand its role in the immune system and its potential as a drug or biomarker.

Protein Name: Ubiquitin Specific Peptidase 9 Y-linked

Functions: May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade. Deubiquitination of SMAD4 by USP9X re-empowers its competence to mediate TGF-beta signaling (By similarity)

The "USP9Y Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about USP9Y comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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