CASK: A Potential Drug Target and Biomarker (G8573)

Target Name: CASK

NCBI ID: G8573

CASK

CASK: A Potential Drug Target and Biomarker

CASK (Protein lin-2 homolog) is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell adhesion and has been implicated in many diseases, including cancer.

One of the most promising aspects of CASK is its potential as a drug target. Researchers have identified several potential drug targets for CASK, including the interaction of CASK with its ligand, EGFR. This interaction suggests that CASK could be a useful target for drugs that are currently being used to treat breast cancer, as well as other types of cancer.

CASK has also been shown to be a potential biomarker for cancer. Its expression has been detected in a variety of cancer types, including breast, ovarian, and prostate cancer. This suggests that CASK could be a useful diagnostic tool for cancer researchers to monitor disease progression and assess the effectiveness of different treatments.

In addition to its potential as a drug target and biomarker, CASK is also of interest to researchers as a potential therapeutic target. Studies have shown that inhibiting the activity of CASK has potential to treat a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the most promising aspects of CASK's potential as a therapeutic target is its involvement in cell signaling pathways.CASK is a key regulator of the RhoA/RhoB GTPase complex, a signaling pathway that regulates cell adhesion and survival. This suggests thatCASK could be a useful target for drugs that are currently being used to treat conditions that are characterized by disrupted cell signaling pathways, such as cancer and neurodegenerative diseases.

Another promising aspect of CASK's potential as a therapeutic target is its involvement in the regulation of cell growth and differentiation.CASK has been shown to play a role in the regulation of cell proliferation and the decision of cell to differentiate into different cell types. This suggests thatCASK could be a useful target for drugs that are currently being used to treat conditions that are characterized by uncontrolled cell growth or unregulated cell differentiation, such as cancer.

In addition to its potential as a drug target and biomarker, CASK is also of interest to researchers as a potential therapeutic target. Studies have shown that inhibiting the activity of CASK has potential to treat a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the most promising aspects of CASK's potential as a therapeutic target is its involvement in cell signaling pathways.CASK is a key regulator of the RhoA/RhoB GTPase complex, a signaling pathway that regulates cell adhesion and survival. This suggests thatCASK could be a useful target for drugs that are currently being used to treat conditions that are characterized by disrupted cell signaling pathways, such as cancer and neurodegenerative diseases.

Another promising aspect of CASK's potential as a therapeutic target is its involvement in the regulation of cell growth and differentiation.CASK has been shown to play a role in the regulation of cell proliferation and the decision of cell to differentiate into different cell types. This suggests thatCASK could be a useful target for drugs that are currently being used to treat conditions that are characterized by uncontrolled cell growth or unregulated cell differentiation, such as cancer.

In addition to its potential as a drug target and biomarker, CASK is also of interest to researchers as a potential therapeutic target. Studies have shown that inhibiting the activity of CASK has potential to treat a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Overall, CASK is a protein that has significant potential as a drug target and biomarker. Its involvement in cell signaling pathways and its ability to regulate cell growth and differentiation make it an attractive target for a variety of diseases. Further research is needed to fully understand the potential of CASK as a therapeutic

Protein Name: Calcium/calmodulin Dependent Serine Protein Kinase

Functions: Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking (PubMed:18423203). Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity)

The "CASK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CASK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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