Target Name: CATSPERE
NCBI ID: G257044
Review Report on CATSPERE Target / Biomarker Content of Review Report on CATSPERE Target / Biomarker
CATSPERE
Other Name(s): CATSPERE variant 2 | uncharacterized protein C1orf101 | Catsper channel auxiliary subunit epsilon, transcript variant 1 | RP11-523K4.1 | cation channel sperm-associated protein subunit epsilon | C1orf101 | CatSperepsilon | Cation channel sperm-associated protein subunit epsilon | catsper channel auxiliary subunit epsilon | catSper-epsilon | C10orf101 | CATSPERE variant 1 | catSperepsilon | Cation channel sperm-associated auxiliary subunit epsilon (isoform 2) | Cation channel sperm-associated auxiliary subunit epsilon (isoform 1) | Catsper channel auxiliary subunit epsilon, transcript variant 2 | CTSRE_HUMAN | CatSper-epsilon

CATSPERE: Key Regulator of Cell Signaling and Pain Perception

CATSPERE (CATSPERE variant 2) is a protein that is expressed in the brain and is involved in the regulation of cell signaling pathways. It is a key regulator of the protein serine/thiosemyin phosphorylation (PTP) and is involved in the formation of neurotransmitter release.

CATSPERE is a member of the superfamily of core histamine antagonist (SHY) proteins, which are characterized by the presence of a characteristic SHY domain and the ability to inhibit the activity of histamine receptors. SHY domains are found in a variety of proteins, including neurotransmitter receptors, G-protein-coupled receptors, and ion channels.

CATSPERE is expressed in the brain and is involved in the regulation of cell signaling pathways, including the regulation of neurotransmitter release and the modulation of pain perception. It is a key regulator of the protein serine/thiosemyin phosphorylation (PTP), which is a critical step in the regulation of neurotransmitter release.

Serine/thiosemyin phosphorylation (PTP) is a critical step in the regulation of neurotransmitter release, as it involves the conversion of the neurotransmitter acetylcholine (ACh) to its active form, acetylcholine (ACh), which is necessary for neurotransmitter release. PTP is regulated by a variety of factors, including the levels of neurotransmitters, the activity of enzymes involved in PTP, and the presence of intracellular signaling molecules.

CATSPERE is involved in the regulation of PTP by the ability to inhibit the activity of the enzyme histidine-protoprotein phosphatase (HPP). HPP is an enzyme involved in the regulation of PTP and is composed of the protein histidine and the protein protoprotein hph.

CATSPERE functions as a negative regulator of HPP by binding to its active site and inhibiting the activity of HPP. This inhibition of HPP activity allows CATSPERE to regulate the levels of neurotransmitters, including serine/thiosemyin, and the modulation of pain perception.

CATSPERE is also involved in the regulation of neurotransmitter release by the ability to modulate the activity of ion channels, including the sodium (Na+) and calcium (Ca2+) channels. This modulation of ion channel activity allows CATSPERE to regulate the levels of neurotransmitters, including serine/thiosemyin, and the modulation of pain perception.

CATSPERE is a potential drug target for the treatment of various neurological disorders, including chronic pain, anxiety and depression. The inhibition of CATSPERE activity by small molecules has been shown to be effective in the modulation of pain perception and the regulation of neurotransmitter release.

In conclusion, CATSPERE is a protein that is involved in the regulation of cell signaling pathways, including the regulation of neurotransmitter release and the modulation of pain perception. It is a key regulator of the protein serine/thiosemyin phosphorylation (PTP) and is a potential drug target for the treatment of various neurological disorders. Further research is needed to fully understand the role of CATSPERE in neurotransmission and the development of effective treatments for associated disorders.

Protein Name: Catsper Channel Auxiliary Subunit Epsilon

Functions: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization

The "CATSPERE Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CATSPERE comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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