CAST as A Cancer Drug Target and Biomarker (G831)

Target Name: CAST

NCBI ID: G831

CAST

CAST as A Cancer Drug Target and Biomarker

Cancer-associated protein (CAP) is a protein that is expressed in various types of cancer, including breast, ovarian, and prostate cancers. It is known to play a role in the development and progression of these diseases. Researchers have been investigating the potential of targeting CAPs as a new drug target or biomarker for cancer treatment. One such target is CAST (CAST variant 14), which is a protein that is expressed in various types of cancer. In this article, we will discuss the research on CAST as a drug target and its potential as a biomarker for cancer treatment.

CAST is a transmembrane protein that is expressed in various types of cancer, including breast, ovarian, and prostate cancers. It is a member of the CAST gene family, which includes several related proteins that are involved in the regulation of cell signaling pathways. CAST is known to play a role in the development and progression of these diseases, and it is thought to contribute to the development of cancer-associated factors (CAs).

One of the key functions of CAST is its role in cell signaling pathways. It is involved in the regulation of several different signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. These pathways are involved in the regulation of cell growth, differentiation, and survival, and are often disrupted in cancer. By targeting these pathways, CAST has been shown to have potential as a drug target for cancer treatment.

In addition to its role in cell signaling pathways, CAST has also been shown to play a role in the regulation of cellular processes that are important for cancer development. For example, studies have shown that CAST is involved in the regulation of cell adhesion, a process that is important for the development of cancer-associated tissues such as tumors. Additionally, CAST has been shown to play a role in the regulation of cell apoptosis, a process that is important for the elimination of damaged or dysfunctional cells.

As a potential drug target, CAST has been shown to have a number of potential benefits as a cancer treatment. For example, studies have shown that inhibiting the activity of CAST can lead to the inhibition of the growth and survival of cancer cells. Additionally, CAST has been shown to play a role in the regulation of cellular processes that are important for cancer development, such as the regulation of cell adhesion and cell apoptosis. This suggests that targeting CAST with drugs that inhibit its activity may be an effective way to treat cancer.

As a potential biomarker, CAST has also been shown to have potential in the diagnosis and prognosis of cancer. For example, studies have shown that the expression of CAST is often increased in cancer cells, and that its expression is associated with the poorer prognosis of cancer patients. Additionally, studies have shown that the expression of CAST is often decreased in cancer-free tissues, and that its decreased expression is associated with a better prognosis of cancer patients. This suggests that targeting CAST with drugs that increase its expression may be an effective way to diagnose and prognose cancer.

In conclusion, CAST is a protein that is expressed in various types of cancer, and it is involved in the regulation of cell signaling pathways and cellular processes that are important for cancer development. As a potential drug target, CAST has been shown to have a number of potential benefits as a cancer treatment, and as a potential biomarker for cancer diagnosis and prognosis. Further research is needed to fully understand the role of CAST as a drug target and biomarker for cancer treatment.

Protein Name: Calpastatin

Functions: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue

The "CAST Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CAST comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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