A Promising Drug Target: CATSPER4 (CatSper4) (G378807)

Target Name: CATSPER4

NCBI ID: G378807

CATSPER4

A Promising Drug Target: CATSPER4 (CatSper4)

Introduction

CATSPER4 (CatSper4), a gene encoding a protein known as cathepsin D (CAT-D), is a member of the cathepsin family, which is a diverse superfamily of proteins involved in various cellular processes. CATSPER4, specifically, has been identified as a potential drug target and biomarker for various diseases, including neurodegenerative disorders, liver diseases, and cancer. This article will provide an overview of CATSPER4, its potential drug target status, and its potential as a biomarker.

CATSPER4: A Putative Drug Target

CATSPER4 is a 21-kDa protein that is expressed in various tissues, including liver, heart, brain, and organs. It is a member of the cathepsin family, which includes proteins that are involved in various cellular processes, including cell signaling, inflammation, and stress response. CATSPER4 is specifically involved in the regulation of cell signaling, as it has been shown to play a role in the signaling pathway known as the TGF-β pathway.

The TGF-β pathway is a well-established signaling pathway that is involved in various cellular processes, including cell growth, differentiation, and inflammation. It is a critical pathway that regulates the growth and development of tissues, and it is also involved in the regulation of stress responses, cell signaling, and inflammation. CATSPER4 has been shown to be involved in the regulation of TGF-β signaling by modulating the activity of the transcription factor, transforminger factor 2 (TF-2).

CATSPER4 has been shown to play a role in the regulation of TGF-β signaling by modulating the activity of the transcription factor, transforminger factor 2 (TF-2).

CATSPER4 as a Potential Biomarker

CATSPER4 has also been identified as a potential biomarker for various diseases, including neurodegenerative disorders, liver diseases, and cancer.

Neurodegenerative Disorders

CATSPER4 has been shown to play a role in the regulation of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These disorders are characterized by the progressive loss of brain cells, leading to the development of various cognitive and motor impairments.

Studies have shown that the levels of CATSPER4 are decreased in the brains of individuals with Alzheimer's disease, and that inhibition of CATSPER4 has been shown to protect against the progression of neurodegenerative disorders. Similarly, CATSPER4 has also been shown to be involved in the regulation of neurotransmitter release in the brain, which is thought to play a role in the development of neurodegenerative disorders.

Liver Diseases

CATSPER4 has also been shown to be involved in the regulation of liver diseases. The liver is an important metabolic and excretory organ in the human body and is also the main target organ for biotransformation drugs. Liver diseases, including hepatitis, cirrhosis, etc., are common diseases that seriously affect human health.

Studies have shown that CATSPER4 is involved in the regulation of cell signaling in the liver, and that its levels are decreased in individuals with liver diseases. In addition, CATSPER4 has been shown to play a role in the regulation of bile acid transport and metabolism, which is thought to be involved in the development of liver diseases.

Cancer

CATSPER4 has also been shown to be involved in the regulation of cancer cell signaling. Cancer is a complex disease that is characterized by the rapid and uncontrolled growth of cells.

Studies have shown that CATSPER4 is involved in the regulation of cell signaling in cancer cells. In addition, CATSPER4 has been shown to play a role in the regulation of cell adhesion, which is thought to be involved in the development of

Protein Name: Cation Channel Sperm Associated 4

Functions: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte

The "CATSPER4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CATSPER4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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