Target Name: NCR2
NCBI ID: G9436
Review Report on NCR2 Target / Biomarker Content of Review Report on NCR2 Target / Biomarker
NCR2
Other Name(s): NK-p44 | lymphocyte antigen 95 (activating NK-receptor; NK-p44) | lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44) | NKP44 | Lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44) | NK cell activating receptor (NKp44) | NCR2 variant 1 | NKp44 | Natural cytotoxicity triggering receptor 2, transcript variant 1 | Natural killer cell p44-related protein | dJ149M18.1 | natural cytotoxicity triggering receptor 2 | CD336 | Lymphocyte antigen 95 (activating NK-receptor; NK-p44) | Lymphocyte antigen 95 homolog | Natural cytotoxicity triggering receptor 2 | Natural cytotoxicity triggering receptor 2 (isoform 1) | LY95 | natural killer cell p44-related protein | NCTR2_HUMAN | NK cell-activating receptor

NCR2: A Protein Involved in Immune Response and Inflammation

NCR2 (NK-p44), a protein that belongs to the non-key protein 44 subfamily of the NK-1 family, plays a critical role in the immune response and inflammation. The NK-1 family is a group of cytoplasmic proteins that are involved in the regulation of cell survival and death, as well as in the immune response.

NCR2 is a 21-kDa protein that is expressed in a variety of tissues, including the brain, spleen, heart, and liver. It is characterized by a N-terminus that contains a short peptide that is similar to the N-terminus of the DNA-binding protein p53. The C-terminus of NCR2 contains a region that is similar to the catalytic domain of a protein that is involved in the detoxification of xenobiotics.

NCR2 is involved in a variety of physiological processes, including the regulation of cell apoptosis, inflammation, and the immune response. One of the well-documented functions of NCR2 is its role in the regulation of cell apoptosis. Apoptosis is a natural process that is involved in the elimination of damaged or dysfunctional cells. NCR2 is involved in the regulation of apoptosis by several mechanisms.

First, NCR2 has been shown to play a role in the regulation of DNA damage-induced apoptosis. DNA damage-induced apoptosis is a critical mechanism of cellular stress response that is involved in the regulation of cell survival. NCR2 is involved in this process by regulating the expression of genes that are involved in DNA repair and by influencing the levels of intracellular reactive oxygen species (ROS).

Second, NCR2 is involved in the regulation of neurodegeneration. Neurodegeneration is a progressive loss of brain cells that is associated with a variety of neurological disorders, including Alzheimer's disease and Parkinson's disease. NCR2 is involved in the regulation of neurodegeneration by several mechanisms. For example, studies have shown that NCR2 is involved in the regulation of neurotransmitter synthesis and release, as well as the regulation of cellular signaling pathways that are involved in neurodegeneration.

Third, NCR2 is involved in the regulation of inflammation. Inflammation is a complex biological response that is involved in the regulation of tissue repair and the prevention of tissue damage. NCR2 is involved in the regulation of inflammation by several mechanisms. For example, studies have shown that NCR2 is involved in the regulation of the production of pro-inflammatory cytokines, as well as the regulation of the expression of anti-inflammatory cytokines.

In addition to its role in the regulation of apoptosis, NCR2 is also involved in the regulation of inflammation and the immune response. For example, studies have shown that NCR2 is involved in the regulation of the production of immune cells, as well as the regulation of the immune response.

Given its involvement in several important physiological processes, NCR2 is an attractive drug target. Researchers have identified several potential drug candidates that are currently being studied for the treatment of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the most promising potential drug targets for NCR2 is the use of inhibitors of the NK-1 receptor, which is a G protein-coupled receptor that is involved in the regulation of cell survival and inflammation. The NK-1 receptor is a potential drug target for several reasons. First, the NK-1 receptor is involved in a variety of physiological processes, including the regulation of cell apoptosis, inflammation, and the immune response. Second, the NK-1 receptor is a strong target for small molecules, which makes it an attractive target for drug development.

Protein Name: Natural Cytotoxicity Triggering Receptor 2

Functions: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis

The "NCR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NCR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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