Understanding The Potential of Native Domain 2 as A Drug Target Or Biomarker

Target Name: ND2

NCBI ID: G4536

Content of Review Report on ND2 Target / Biomarker

ND2

Understanding The Potential of Native Domain 2 as A Drug Target Or Biomarker

Native Domain 2 (ND2) is a protein that is expressed in various tissues throughout the body, including the nervous system. It is a key regulator of neuronal function and has been implicated in a number of neurological and psychiatric disorders. In recent years, researchers have been investigating ND2 as a potential drug target or biomarker for a variety of neurological conditions, including Alzheimer's disease, Parkinson's disease, and depression.

The research on ND2 began in the 1990s when scientists identified the protein in the brain that was responsible for the production of a neurotransmitter called dopamine. Dopamine is a chemical that is involved in the pleasure and reward centers of the brain, and it is often Abnormal levels of dopamine have been linked to a number of neurological disorders, including Parkinson's disease and Alzheimer's disease.

Following the discovery of ND2, researchers began to investigate its role in the regulation of neuronal function. They found that ND2 was highly expressed in the brain and that it was involved in the production of dopamine. They also found that ND2 was regulated by several different factors, including the neurotransmitter GABA and the protein brain-derived neurotrophic factor (BDNF).

In addition to its role in the production of dopamine, ND2 has also been shown to play a number of other important roles in the regulation of neuronal function. For example, it has been shown to regulate the migration and survival of neurons, as well as the formation and maintenance of neural connections. It has also been shown to play a role in the regulation of ion channels and neurotransmitter release.

Despite these promising findings, much more research is needed before ND2 can be fully understood as a drug target or biomarker. For example, it is not yet clear exactly how ND2 interacts with other proteins in the brain, or how it is involved in the development of certain neurological disorders. Additionally, there are concerns thatND2 may be involved in a number of other biological processes that are not yet fully understood, which could limit its potential as a drug target or biomarker.

In conclusion, ND2 is a protein that has great potential as a drug target or biomarker for a variety of neurological conditions. Its role in the regulation of neuronal function and its involvement in the production of dopamine make it an attractive target for drug development. Further research is needed to fully understand its role in the regulation of brain function and its potential as a drug or biomarker.

Protein Name: Mitochondrially Encoded NADH Dehydrogenase 2

Functions: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:16996290). Essential for the catalytic activity and assembly of complex I (PubMed:16996290)

The "ND2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ND2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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