GPR50: AG Protein-Coupled Receptor in Sleep-Wake Cycle, Pain Perception and Neurotransmitter Signaling

Target Name: GPR50

NCBI ID: G9248

GPR50

Other Name(s): Melatonin-related receptor | MTR1L_HUMAN | G protein-coupled receptor 50 | H9 | Mel1c

GPR50: AG Protein-Coupled Receptor in Sleep-Wake Cycle, Pain Perception and Neurotransmitter Signaling

GPR50 (G protein-coupled receptor 50) is a transmembrane receptor that is expressed in various tissues and cells throughout the body. It is involved in the regulation of various physiological processes, including sleep-wake cycle, pain perception, and neurotransmitter signaling. GPR50 has also been implicated in various neurological and psychiatric disorders, making it an attractive drug target in the field of pharmacology.

GPR50 is a G protein-coupled receptor, which means that it is composed of a extracellular domain that is responsible for interacting with ligands, a transmembrane region that spans the cell membrane, and an intracellular domain that contains the catalytic and regulatory activities of the receptor. The G protein-coupled receptor is a family of transmembrane proteins that play a crucial role in cellular signaling. They are involved in the regulation of various physiological processes, including sensory perception, neurotransmitter signaling, and cell survival. GPR50 is one of the G protein-coupled receptors that has been extensively studied, and its function is still not fully understood.

GPR50 is involved in the regulation of the sleep-wake cycle, which is the process by which the body switching between wakefulness and sleep. During the sleep phase, GPR50 is expressed in the brain and is involved in the regulation of the sleep-wake cycle. Studies have shown that GPR50 plays a crucial role in the regulation of sleep-wake cycle, and that it is involved in the development of various sleep disorders, including insomnia and sleep apnea.

GPR50 is also involved in the regulation of pain perception. Pain is a highly unpleasant physical sensation that is associated with various physiological and psychological processes. GPR50 is involved in the regulation of pain perception, and studies have shown that GPR50 plays a negative role in the regulation of pain. GPR50 has been shown to interact with nociceitin, a potent pain mediator that is involved in pain perception. The interaction between GPR50 and nociceitin has been shown to play a role in the regulation of pain perception.

GPR50 is also involved in the regulation of neurotransmitter signaling. Neurotransmitters are essential for the regulation of various physiological processes, including mood, anxiety, and pain. GPR50 is involved in the regulation of neurotransmitter signaling, and studies have shown that GPR50 plays a crucial role in the regulation of neurotransmitter signaling. GPR50 has been shown to interact with dopamine, a neurotransmitter that is involved in mood, anxiety, and pain. The interaction between GPR50 and dopamine has been shown to play a role in the regulation of neurotransmitter signaling.

GPR50 is also involved in the regulation of cell survival. Cell survival is essential for the regulation of various physiological processes, including growth, differentiation, and repair. GPR50 is involved in the regulation of cell survival, and studies have shown that GPR50 plays a crucial role in the regulation of cell survival. GPR50 has been shown to interact with p53, a protein that is involved in cell survival. The interaction between GPR50 and p53 has been shown to play a role in the regulation of cell survival.

In conclusion, GPR50 is a G protein-coupled receptor that is involved in the regulation of various physiological processes. GPR50 has been shown to be involved in the regulation of the sleep-wake cycle, pain perception, neurotransmitter signaling, and cell survival. As a result, GPR50 is an attractive drug target in the field of pharmacology. The development of compounds that can selectively interact with GPR50 and modulate its function may lead to the development of new treatments for various psychiatric and neurological disorders.

Protein Name: G Protein-coupled Receptor 50

Functions: Does not bind melatonin

The "GPR50 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR50 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets