MAD2L1BP: Regulating P53, P16INK4a and NF-kappa-B (G9587)

Target Name: MAD2L1BP

NCBI ID: G9587

MAD2L1BP

MAD2L1BP: Regulating P53, P16INK4a and NF-kappa-B

MAD2L1BP (MAD2L1-associated protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and gastrointestinal tract. It is a member of the MAD2L1 family of proteins, which are known for their role in intracellular signaling. One of the functions of MAD2L1BP is to interact with the protein MAD2L1, which is also known as MAD2L1-associated protein.

The MAD2L1BP protein is involved in a variety of cellular processes that are important for normal development, growth, and function. One of the main functions of MAD2L1BP is to regulate the activity of the transcription factor, p53. P53 is a well-known protein that is involved in the regulation of gene expression, and it is often activated in response to DNA damage or other stressors. MAD2L1BP helps to regulate the activity of p53 by binding to its DNA-binding domain and preventing it from binding to certain target genes.

Another function of MAD2L1BP is to regulate the activity of the protein, p16INK4a. p16INK4a is a gene that is involved in the regulation of cell growth, and it is often activated in response to the presence of cancer cells. MAD2L1BP helps to regulate the activity of p16INK4a by binding to its nuclear-binding domain and preventing it from binding to certain target genes.

MAD2L1BP is also involved in the regulation of the activity of the protein, NF-kappa-B. NF-kappa-B is a protein that is involved in the regulation of inflammation and other cellular processes. MAD2L1BP helps to regulate the activity of NF-kappa-B by binding to its nuclear-binding domain and preventing it from binding to certain target genes.

In addition to its role in regulating the activity of p53, p16INK4a, and NF-kappa-B, MAD2L1BP is also involved in the regulation of the activity of other proteins. It is a component of the protein complex known as the MAD2L1-associated complex, which is involved in the regulation of the activity of these proteins. MAD2L1BP is also known as the protein 尾 (p21), which is a subunit of the protein complex known as the T-cell factor (TFF) complex.

MAD2L1BP is also expressed in various tissues throughout the body, including the brain, heart, and gastrointestinal tract. It is found in the brain, where it is involved in the regulation of the activity of the neurotransmitter, dopamine. It is also found in the heart, where it is involved in the regulation of the contractility of the heart muscle. Additionally, MAD2L1BP is found in the gastrointestinal tract, where it is involved in the regulation of the secretion of digestive enzymes.

In conclusion, MAD2L1BP is a protein that is involved in a variety of cellular processes that are important for normal development, growth, and function. It is a member of the MAD2L1 family of proteins and is involved in the regulation of the activity of p53, p16INK4a, and NF-kappa-B. MAD2L1BP is also involved in the regulation of the activity of other proteins and is expressed in various tissues throughout the body. Given its involvement in these processes, MAD2L1BP may be a drug target or biomarker for a variety of diseases.

Protein Name: MAD2L1 Binding Protein

Functions: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex

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