MALSU1: A Drug Target and Biomarker for Mitochondrial Function

Target Name: MALSU1

NCBI ID: G115416

MALSU1

MALSU1: A Drug Target and Biomarker for Mitochondrial Function

Mitochondria are organelles responsible for generating energy in the form of ATP in cells throughout the body. They are also involved in the production of proteins, including ribosomal large subunit 1 (Rls1), which is a key component of the mitochondrial ribosome. MALSU1, a protein that plays a crucial role in the assembly of Rls1, has recently been identified as a potential drug target and biomarker for mitochondrial function.

Mitochondria are complex organelles that consist of a core and an outer membrane. The cytoplasm contains the mitochondrial DNA, while the mitochondrial membrane adds to the cytoplasm. The mitochondrial ribosome is the small organelle responsible for protein synthesis in the cell. It is composed of a large subunit (Rls) and an smaller subunit (rRNA), which are held together by a complex of proteins, including MALSU1.

MALSU1 is a protein that contains 154 amino acids and is located at the cytoplasmic side of the mitochondrial ribosome. It is part of the outer membrane of the ribosome and is involved in the assembly of Rls1. Rls1 is a large subunit of the ribosome that is responsible for forming the matrix for protein synthesis. It is composed of two subunits, Rls1a and Rls1b, which are held together by a complex of proteins, including MALSU1.

MALSU1 functions as a protein that helps to assemble Rls1. It does this by playing a structural role in the assembly process. MALSU1 contains a unique domain that is specific to the assembly of Rls1. This domain is composed of a unique sequence of amino acids that is involved in the formation of a complex with Rls1a. This complex is thought to play a key role in the assembly of Rls1 by allowing MALSU1 to interact with Rls1a in a specific way.

In addition to its role in the assembly of Rls1, MALSU1 is also involved in the regulation of mitochondrial function. It is has also been shown to play a role in the biogenesis of mitochondria and in the regulation of mitochondrial dynamics. be involved in the negative regulation of mitochondrial fission, which is the process by which mitochondria divide.

MALSU1 has also been shown to be involved in the regulation of mitochondrial dynamics. It is has been shown to play a role in the regulation of mitochondrial traffic, which is the movement of mitochondria from the cytoplasm to the mitochondrial membrane. MALSU1 is also thought to be involved in the regulation of mitochondrial fusion, which is the process by which two mitochondria fuse to form one.

MALSU1 has also been shown to play a role in the regulation of cellular processes that are independent of mitochondrial function. It is has been shown to be involved in the regulation of cytoskeletal organization, which is the structure of the cytoskeleton in the cell. MALSU1 is also thought to be involved in the regulation of cell adhesion, which is the process by which cells stick together and form tissues.

In conclusion, MALSU1 is a protein that plays a crucial role in the assembly of the mitochondrial ribosome. It is also involved in the regulation of mitochondrial function and in the regulation of cellular processes that are independent of mitochondrial function. Its unique structure and function make it an attractive target for drug development. Further research is needed to fully understand the role of MALSU1 in the regulation of mitochondrial function and to determine its potential as a drug.

Protein Name: Mitochondrial Assembly Of Ribosomal Large Subunit 1

Functions: Required for normal mitochondrial ribosome function and mitochondrial translation (PubMed:22238375, PubMed:23171548). May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (PubMed:22238376, PubMed:23171548). May function as a ribosomal silencing factor (Probable)

The "MALSU1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MALSU1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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