MAGEB3: A Protein Involved in Immune Response and Inflammation

Target Name: MAGEB3

NCBI ID: G4114

MAGEB3

MAGEB3: A Protein Involved in Immune Response and Inflammation

MAGEB3, also known as MAGEB3IP3, is a gene that encodes a protein known as MAGEB3. MAGEB3 is a member of the MAGE family of proteins, which are involved in the immune response and inflammation. The MAGE family of proteins are known for their ability to induce an immune response against a wide variety of microbial and viral pathogens, as well as cancer cells.

MAGEB3 is a 24-kDa protein that is expressed in a variety of tissues throughout the body, including the skin, hair, and nails. It is primarily localized to the cytoplasm of cells, where it can interact with and modulate the activity of various cellular signaling pathways.

One of the key functions of MAGEB3 is its role in the immune response. MAGEB3 has been shown to play a key role in the regulation of T cell development and function. Specifically, MAGEB3 has been shown to be involved in the negative regulation of CD4+ T cell development, as well as the regulation of CD8+ T cell responses to viruses and cancer cells.

In addition to its role in T cell development, MAGEB3 has also been shown to play a key role in the regulation of inflammation. Specifically, MAGEB3 has been shown to be involved in the regulation of the production and function of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾.

MAGEB3 is also known as a potential drug target for several diseases, including cancer, autoimmune diseases, and inflammatory disorders. For example, MAGEB3 has been shown to be involved in the regulation of the development and progression of skin cancer, and has been shown to be downregulated in a variety of cancer cells. Additionally, MAGEB3 has been shown to be involved in the regulation of autoimmune diseases, including rheumatoid arthritis and multiple sclerosis.

In conclusion, MAGEB3 is a protein that has important roles in both the immune response and inflammation. Its potential as a drug target makes it an attractive target for the development of new therapies for a variety of diseases. Further research is needed to fully understand the functions of MAGEB3 and its potential as a drug.

Protein Name: MAGE Family Member B3

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•   general information;
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