Target Name: MAK
NCBI ID: G4117
Review Report on MAK Target / Biomarker Content of Review Report on MAK Target / Biomarker
MAK
Other Name(s): serine/threonine protein kinase MAK | Testicular secretory protein Li 28 | Male germ cell-associated kinase | MAK variant 3 | male germ cell associated kinase | Serine/threonine-protein kinase MAK (isoform 3) | Male germ cell associated kinase, transcript variant 3 | Male germ cell associated kinase, transcript variant 2 | RP62 | Serine/threonine-protein kinase MAK | DJ417M14.2 | Male germ cell-associated kinase retinal-enriched isoform | OTTHUMP00000016025 | testicular secretory protein Li 28 | Serine/threonine protein kinase MAK | MAK_HUMAN | MAK variant 2 | Serine/threonine-protein kinase MAK (isoform 2)

MAK: A Protein Targeted for Cancer and Neurodegenerative Diseases

MAK (serine/threonine protein kinase) is a protein that plays a crucial role in cell signaling pathways. It is a key regulator of many cellular processes, including cell growth, differentiation, and survival. MAK has been identified as a potential drug target and is currently being targeted by researchers for the development of new treatments for various diseases.

MAK is a protein that is expressed in many different cell types, including neurons, muscle cells, and cancer cells. It is a serine/threonine protein kinase, which means that it catalyzes the transfer of a phosphate group from a serine or threonine protein to its target protein. This transfer of phosphates is a critical process in cell signaling, as it allows cells to communicate with each other and to respond to different stimuli.

MAK is involved in many different cellular processes. For example, it is involved in the regulation of cell growth, which is critical for the development and maintenance of tissues and organs. MAK also plays a role in the regulation of cell differentiation, which is the process by which cells become specialized cells with unique functions. Additionally, MAK is involved in the regulation of cell survival, as it plays a role in the process of apoptosis, which is the programmed cell death that occurs when a cell is no longer able to function properly.

MAK has also been identified as a potential drug target for several diseases. For example, MAK has been shown to be involved in the development and progression of cancer, which is a leading cause of death in the United States. Researchers have found that high levels of MAK are associated with poor prognosis in cancer patients. Additionally, MAK has also been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases.

In addition to its potential as a drug target, MAK is also being studied as a biomarker. This is because it is a protein that is expressed in many different cell types, which makes it a potential indicator of the health of those cells. Researchers have found that levels of MAK are often elevated in the brains of people with neurodegenerative diseases, which suggests that MAK may be a useful biomarker for these conditions.

Another potential use for MAK is as a therapeutic target. Researchers are currently working on developing new treatments for MAK-related diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. These treatments are designed to target MAK and to inhibit its activity, which may help to reduce the growth and spread of cancer cells, slow the progression of neurodegenerative diseases, and treat autoimmune disorders.

In conclusion, MAK is a protein that plays a crucial role in cell signaling pathways. It is a key regulator of many cellular processes, including cell growth, differentiation, and survival. As a result, it has been identified as a potential drug target and is currently being targeted by researchers for the development of new treatments for various diseases. Additionally, MAK is also being studied as a biomarker, which may have implications for the development of new diagnostic tests for neurodegenerative diseases.

Protein Name: Male Germ Cell Associated Kinase

Functions: Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells

The "MAK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MAK16 | MAL | MAL2 | MALAT1 | Malate dehydrogenase | MALL | MALLP2 | MALRD1 | MALSU1 | MALT1 | MAMDC2 | MAMDC2-AS1 | MAMDC4 | MAML1 | MAML2 | MAML3 | MAMLD1 | MAMSTR | MAN1A1 | MAN1A2 | MAN1B1 | MAN1B1-DT | MAN1C1 | MAN2A1 | MAN2A2 | MAN2B1 | MAN2B2 | MAN2C1 | MANBA | MANBAL | MANCR | MANEA | MANEA-DT | MANEAL | MANF | MANSC1 | MANSC4 | MAOA | MAOB | MAP10 | MAP1A | MAP1B | MAP1LC3A | MAP1LC3B | MAP1LC3B2 | MAP1LC3BP1 | MAP1LC3C | MAP1S | MAP2 | MAP2K1 | MAP2K1P1 | MAP2K2 | MAP2K3 | MAP2K4 | MAP2K4P1 | MAP2K5 | MAP2K6 | MAP2K7 | MAP3K1 | MAP3K10 | MAP3K11 | MAP3K12 | MAP3K13 | MAP3K14 | MAP3K14-AS1 | MAP3K15 | MAP3K19 | MAP3K2 | MAP3K2-DT | MAP3K20 | MAP3K20-AS1 | MAP3K21 | MAP3K3 | MAP3K4 | MAP3K5 | MAP3K5-AS2 | MAP3K6 | MAP3K7 | MAP3K7CL | MAP3K8 | MAP3K9 | MAP3K9-DT | MAP4 | MAP4K1 | MAP4K1-AS1 | MAP4K2 | MAP4K3 | MAP4K3-DT | MAP4K4 | MAP4K5 | MAP6 | MAP6D1 | MAP7 | MAP7D1 | MAP7D2 | MAP7D3 | MAP9 | MAPK1 | MAPK10 | MAPK10-AS1