MAGED4B: A Protein Targeted for Drug Development (G81557)

Target Name: MAGED4B

NCBI ID: G81557

MAGED4B

MAGED4B: A Protein Targeted for Drug Development

MAGED4B, also known as OTTHUMP00000023307, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the magenin family, which is a group of transmembrane proteins that play a crucial role in various cellular processes.

One of the most significant functions of MAGED4B is its role in the regulation of cell signaling pathways. MAGED4B is known to interact with several different signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. These signaling pathways are involved in a wide range of cellular processes, including cell growth, differentiation, and inflammation.

MAGED4B is also known to play a role in the regulation of cellular transport processes. It is involved in the transport of various molecules, including neurotransmitters and ion channels, to and from the cell membrane. This function is critical for the proper functioning of many cellular processes, including neurotransmission and muscle contractions.

In addition to its role in cell signaling and transport processes, MAGED4B is also known to play a role in the regulation of cellular adhesion. Adhesion is the process by which cells stick together to form tissues and organs. MAGED4B is involved in the formation of tight junctions, which are a type of cell-cell adhesion structure, and in the regulation of cell-cell adhesion by the protein cadherin.

MAGED4B is also an attractive drug target due to its unique structure and the various functions it is involved in. The magenin family of proteins is known for their ability to interact with a wide range of molecules, making them a promising target for drug development. In addition, MAGED4B is also known to be involved in several diseases, including cancer and neurodegenerative diseases.

Despite the potential benefits of MAGED4B as a drug target, there are also several concerns about its safety and effectiveness. The use of MAGED4B as a drug may be associated with several potential side effects, including muscle weakness, neurotoxicity, and cardiovascular problems. In addition, there is limited research on the specific effects of MAGED4B at a drug target, which may limit its effectiveness in treating certain diseases.

Despite these concerns, MAGED4B is a protein that is still being studied for its potential as a drug target. Researchers are working to better understand its functions and to identify new ways to use it as a treatment. As research continues, it is likely that MAGED4B will become a valuable tool for the treatment of a wide range of diseases.

Protein Name: MAGE Family Member D4B

Functions: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex

The "MAGED4B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAGED4B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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