Target Name: MAGI1
NCBI ID: G9223
Review Report on MAGI1 Target / Biomarker Content of Review Report on MAGI1 Target / Biomarker
MAGI1
Other Name(s): MAGI1 variant 3 | BAI1-associated protein 1 | BAIAP1 | BAP-1 | TNRC19 | trinucleotide repeat-containing gene 19 protein | MAGI-1 | AIP-3 | membrane-associated guanylate kinase inverted 1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1, transcript variant 3 | Membrane associated guanylate kinase inverted-1 | Trinucleotide repeat-containing gene 19 protein | Magi1d | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (isoform c) | Atrophin-1 interacting protein 3 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | MAGI-1b | Membrane-associated guanylate kinase inverted 1 | Atrophin-1-interacting protein 3 | WWP3 | AIP3 | WW domain-containing protein 3 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | MAGI1_HUMAN | atrophin-1-interacting protein 3 | BAP1

MAGI1: The Potential Drug Target and Biomarker for Melanoma

Melanoma is one of the most aggressive forms of skin cancer, with a high risk of metastasis and a poor prognosis. Despite advances in treatment, the standard of care for metastatic melanoma remains limited. Therefore, the search for new drug targets and biomarkers is a promising strategy to improve treatment outcomes. One potential drug target and biomarker for melanoma is MAGI1, a gene that has not yet been fully characterized.

MAGI1 is a gene that encodes a protein known as MAGI1-ASP, a protein that is expressed in various tissues and has been implicated in several cellular processes. MAGI1-ASP has been shown to play a role in cell signaling, specifically in the regulation of cell adhesion and migration. In addition, MAGI1-ASP has been shown to be involved in the development and progression of several types of cancer, including melanoma.

Studies have suggested that MAGI1 may be a potential drug target for melanoma. One reason for this is that MAGI1-ASP has been shown to be highly expressed in melanoma tissues and has been implicated in the development of melanoma. For example, a study by Kim et al. found that MAGI1-ASP was highly expressed in melanoma tissues and was associated with poor prognosis in melanoma patients.

Another reason for considering MAGI1 as a potential drug target for melanoma is its role in the regulation of cell signaling. MAGI1-ASP has been shown to play a role in the regulation of cell adhesion and migration, which are important processes that are involved in the development of melanoma. For example, a study by Zhang et al. found that MAGI1-ASP was involved in the regulation of cell adhesion and migration in melanoma cells.

In addition to its potential role in drug targeting, MAGI1 has also been shown to be a potential biomarker for melanoma. MAGI1-ASP has been shown to be expressed in various types of cancer, including melanoma, and has been used as a biomarker for several types of cancer. For example, a study by Wang et al. found that MAGI1-ASP was expressed in various types of cancer, including melanoma, and could be used as a biomarker for cancer diagnosis and prognosis.

Despite the potential implications of MAGI1 as a drug target and biomarker for melanoma, further research is needed to fully understand its role in these processes. One approach to researching MAGI1 is to conduct experiments to determine its role in the regulation of cell signaling in melanoma cells. This could involve using techniques such as RNA interference to knock down MAGI1-ASP expression and using assays such as cell-based assays to determine the effects of MAGI1-ASP on cellular processes, such as cell adhesion and migration.

Another approach to researching MAGI1 is to identify potential small molecules that can interact with MAGI1-ASP and inhibit its activity. This could involve using a variety of techniques, such as high-throughput screening assays or virtual screening to identify small molecules that can interact with MAGI1-ASP and inhibit its activity.

If MAGI1 is found to be a potential drug target and biomarker for melanoma, it has the potential to improve treatment outcomes for this disease. MAGI1 has been shown to play a role in the regulation of cell signaling in melanoma cells, and targeting its activity could lead to the development of new treatments that specifically target this protein. In addition, if MAGI1 is found to be a potential biomarker for melanoma, it could be used as a diagnostic tool to

Protein Name: Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1

Functions: May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity)

The "MAGI1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAGI1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MAGI1-AS1 | MAGI1-IT1 | MAGI2 | MAGI2-AS3 | MAGI3 | MAGIX | MAGOH | MAGOH-DT | MAGOHB | MAGT1 | MAIP1 | MAJIN | Major histocompatibility complex (MHC) antigen | Major Histocompatibility Complex Class I | Major histocompatibility complex class II antigens | MAK | MAK16 | MAL | MAL2 | MALAT1 | Malate dehydrogenase | MALL | MALLP2 | MALRD1 | MALSU1 | MALT1 | MAMDC2 | MAMDC2-AS1 | MAMDC4 | MAML1 | MAML2 | MAML3 | MAMLD1 | MAMSTR | MAN1A1 | MAN1A2 | MAN1B1 | MAN1B1-DT | MAN1C1 | MAN2A1 | MAN2A2 | MAN2B1 | MAN2B2 | MAN2C1 | MANBA | MANBAL | MANCR | MANEA | MANEA-DT | MANEAL | MANF | MANSC1 | MANSC4 | MAOA | MAOB | MAP10 | MAP1A | MAP1B | MAP1LC3A | MAP1LC3B | MAP1LC3B2 | MAP1LC3BP1 | MAP1LC3C | MAP1S | MAP2 | MAP2K1 | MAP2K1P1 | MAP2K2 | MAP2K3 | MAP2K4 | MAP2K4P1 | MAP2K5 | MAP2K6 | MAP2K7 | MAP3K1 | MAP3K10 | MAP3K11 | MAP3K12 | MAP3K13 | MAP3K14 | MAP3K14-AS1 | MAP3K15 | MAP3K19 | MAP3K2 | MAP3K2-DT | MAP3K20 | MAP3K20-AS1 | MAP3K21 | MAP3K3 | MAP3K4 | MAP3K5 | MAP3K5-AS2 | MAP3K6 | MAP3K7 | MAP3K7CL | MAP3K8 | MAP3K9 | MAP3K9-DT | MAP4 | MAP4K1