Understanding MAML2: Potential Drug Target for Various Diseases

Target Name: MAML2

NCBI ID: G84441

MAML2

Understanding MAML2: Potential Drug Target for Various Diseases

MAML2 (MAML3), also known as GFR伪1-36, is a protein that is expressed in almost all human tissues and plays a critical role in cell signaling. It is a member of the G protein-coupled receptor (GPCR) family and is involved in various physiological processes such as cell growth, differentiation, and survival.

MAML2 is a potential drug target and has been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has led to a growing interest in developing compounds that can selectively target MAML2 and modulate its activity.

One of the major challenges in studying MAML2 is its complex structure and the various interactions it has with other proteins. Despite its importance, MAML2 has only been studied to a limited extent, and many aspects of its biology are still poorly understood.

One of the well-known functions of MAML2 is its role in cell signaling. It is a GPCR and its activity is regulated by various intracellular signaling pathways. MAML2 has been shown to play a role in several signaling pathways, including the TGF-β pathway , the PI3K/Akt pathway, and the NF-kappa-B pathway.

MAML2 has also been shown to be involved in cell adhesion and migration. It has been shown to be a critical regulator of the adhesion protein (integrin) family, which is involved in cell adhesion and migration. MAML2 has been shown to play a role in the regulation of cell adhesion by integratingins, such as CD73 and PDZ1.

In addition to its role in cell signaling, MAML2 has also been shown to be involved in the regulation of cellular processes such as cell cycle progression, apoptosis, and cellular stress. It has been shown to play a role in the regulation of the G1/ S transition, the G2/M transition, and the G0/G1 transition.

MAML2 has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of inflammatory responses and has been shown to play a negative role in the regulation of inflammation.

In conclusion, MAML2 is a protein that has been shown to play a critical role in several physiological processes, including cell signaling, cell adhesion and migration, and inflammation. As a potential drug target, MAML2 has the potential to be developed into a new treatment for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of MAML2 and to develop compounds that can selectively target it.

Protein Name: Mastermind Like Transcriptional Coactivator 2

Functions: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3

The "MAML2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAML2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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