Man2b1: Key Regulator of Brain Development and Function (G4125)

Target Name: MAN2B1

NCBI ID: G4125

MAN2B1

Man2b1: Key Regulator of Brain Development and Function

MAN2B1 (Lysosomal alpha-mannosidase D peptide) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and liver. It is a key component of the lysosome, a organelle that is responsible for the degradation of damaged or unnecessary cellular components. Man2b1 has been shown to play a role in the regulation of cellular processes that are important for brain development and function, including the regulation of neurotransmitter release and the modulation of inflammation.

One of the unique features of Man2b1 is its ability to interact with other proteins that are expressed in the same cell. This interaction allows Man2b1 to regulate the activity of these other proteins, which can have a wide range of effects on cellular processes. For example, Man2b1 has been shown to interact with the protein known asBeclin-1, which is involved in the regulation of mitochondrial function and cell death. This interaction between Man2b1 and Beclin-1 has been shown to play a role in the regulation of brain development and function.

Another interesting feature of Man2b1 is its ability to interact with the protein known as ALIX. This interaction between Man2b1 and ALIX has been shown to play a role in the regulation of cellular processes that are important for the development and maintenance of the blood-brain barrier. The blood-brain barrier is a specialized barrier that separates the brain from the blood, and it plays a critical role in the exchange of nutrients, oxygen, and other substances between the brain and the bloodstream. Man2b1 has been shown to interact with ALIX in a way that allows it to regulate the formation and maintenance of the blood-brain barrier, which can have important implications for the treatment of various neurological disorders.

In addition to its role in the regulation of cellular processes, Man2b1 has also been shown to play a role in the development and progression of certain diseases. For example, Man2b1 has been shown to be involved in the regulation of the production of amyloid peptides, which are a hallmark of Alzheimer's disease. These peptides are thought to play a role in the destruction of brain cells in the progression of Alzheimer's disease, and Man2b1 has been shown to interact with the protein known as A尾21, which is thought to contribute to the production of these peptides.

Another potential drug target for Man2b1 is its ability to interact with the protein known as CD47. This interaction between Man2b1 and CD47 has been shown to play a role in the regulation of cellular processes that are important for the development and maintenance of blood cells. CD47 is a protein that is expressed in the bone marrow and is involved in the regulation of the production and function of red blood cells. Man2b1 has been shown to interact with CD47 in a way that allows it to regulate the production of CD47 in the bone marrow, which can have important implications for the treatment of various hematological disorders.

In conclusion, Man2b1 is a protein that has been shown to play a critical role in the regulation of various cellular processes that are important for brain development and function. Its ability to interact with other proteins and its involvement in the regulation of cellular processes that are important for the development and progression of certain diseases make it an attractive potential drug target. Further research is needed to fully understand the role of Man2b1 in cellular processes and its potential as a drug target.

Protein Name: Mannosidase Alpha Class 2B Member 1

Functions: Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages

The "MAN2B1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAN2B1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets