Target Name: MAN1C1
NCBI ID: G57134
Review Report on MAN1C1 Target / Biomarker Content of Review Report on MAN1C1 Target / Biomarker
MAN1C1
Other Name(s): MA1C1_HUMAN | Mannosidase alpha class 1C member 1 | OTTHUMP00000004645 | HMIC | OTTHUMP00000004643 | Processing alpha-1,2-mannosidase IC | 1,2-alpha-mannosidase IC | Pp6318 | MAN1C | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (isoform 1) | mannosidase alpha class 1C member 1 | OTTHUMP00000004644 | processing alpha-1,2-mannosidase IC | MAN1C1 variant 1 | Mannosidase alpha class 1C member 1, transcript variant 1 | Alpha-1,2-mannosidase IC | MAN1A3 | pp6318

MAN1C1: A Potential Drug Target Or Biomarker

MAN1C1 (MA1C1_HUMAN), a protein that is expressed in various tissues of the human body, has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

MAN1C1 is a member of the IMP-1 (Inositol-Mannoside 1) family, which is a group of transmembrane proteins that play a crucial role in various cellular processes, including intracellular signaling, cytoskeletal organization, and neurotransmission. The IMP-1 family has has been implicated in a wide range of physiological processes, including cell survival, growth, and differentiation, as well as modulating cellular signaling pathways.

Recent studies have identified MAN1C1 as a potential drug target or biomarker due to its involvement in several diseases. For example, increased levels of MAN1C1 have been observed in various tissues of cancer patients, and downregulated levels have been detected in neurodegenerative diseases, suggesting that it may play a role in the development and progression of these conditions. Additionally, studies have shown that MAN1C1 is involved in the regulation of cellular signaling pathways that are involved in a wide range of physiological processes, including cell survival, angiogenesis, and inflammation.

Furthermore, MAN1C1 has also been shown to be involved in the regulation of cellular interactions with the extracellular matrix (ECM), which is a complex system of interacting molecules that plays a crucial role in maintaining tissue structure and function. ECM components, including collagen , elastin and fibronectin, etc., can affect the physical properties and biological activity of the extracellular matrix, thereby affecting the interaction between cells and the surrounding environment. Therefore, studying the role of MAN1C1 in ECM will help people better understand the relationship between cells and the surrounding environment, and provide new ideas for the development of new treatments.

In addition, MAN1C1 is also closely related to the occurrence and development of some diseases. For example, studies have shown that the activity and expression levels of MAN1C1 are positively correlated with a variety of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, indicating that MAN1C1 may be closely related to the occurrence and development of these diseases. Related. In addition, MAN1C1 is also closely related to the regulation of the immune system and participates in the regulation of the differentiation and function of immune cells. It may have potential application value in the treatment of immune-related diseases.

Therefore, MAN1C1, as a protein, has broad application prospects. In-depth study of the role of MAN1C1 in disease can provide new ideas for the development of new treatment methods and is expected to bring more benefits to human health. At the same time, the study of MAN1C1 will also provide an important theoretical basis for in-depth understanding of the role of IMP-1 family proteins in biomedical research.

Protein Name: Mannosidase Alpha Class 1C Member 1

Functions: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc

The "MAN1C1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MAN1C1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MAN2A1 | MAN2A2 | MAN2B1 | MAN2B2 | MAN2C1 | MANBA | MANBAL | MANCR | MANEA | MANEA-DT | MANEAL | MANF | MANSC1 | MANSC4 | MAOA | MAOB | MAP10 | MAP1A | MAP1B | MAP1LC3A | MAP1LC3B | MAP1LC3B2 | MAP1LC3BP1 | MAP1LC3C | MAP1S | MAP2 | MAP2K1 | MAP2K1P1 | MAP2K2 | MAP2K3 | MAP2K4 | MAP2K4P1 | MAP2K5 | MAP2K6 | MAP2K7 | MAP3K1 | MAP3K10 | MAP3K11 | MAP3K12 | MAP3K13 | MAP3K14 | MAP3K14-AS1 | MAP3K15 | MAP3K19 | MAP3K2 | MAP3K2-DT | MAP3K20 | MAP3K20-AS1 | MAP3K21 | MAP3K3 | MAP3K4 | MAP3K5 | MAP3K5-AS2 | MAP3K6 | MAP3K7 | MAP3K7CL | MAP3K8 | MAP3K9 | MAP3K9-DT | MAP4 | MAP4K1 | MAP4K1-AS1 | MAP4K2 | MAP4K3 | MAP4K3-DT | MAP4K4 | MAP4K5 | MAP6 | MAP6D1 | MAP7 | MAP7D1 | MAP7D2 | MAP7D3 | MAP9 | MAPK1 | MAPK10 | MAPK10-AS1 | MAPK11 | MAPK12 | MAPK13 | MAPK14 | MAPK15 | MAPK1IP1L | MAPK3 | MAPK4 | MAPK6 | MAPK6P2 | MAPK7 | MAPK8 | MAPK8IP1 | MAPK8IP1P2 | MAPK8IP2 | MAPK8IP3 | MAPK9 | MAPKAP1 | MAPKAPK2 | MAPKAPK3 | MAPKAPK5 | MAPKAPK5-AS1 | MAPKBP1