Target Name: GAB4
NCBI ID: G128954
Review Report on GAB4 Target / Biomarker Content of Review Report on GAB4 Target / Biomarker
GAB4
Other Name(s): GRB2-associated binder 2-like protein | GAB4 variant 1 | GRB2-associated binder 2-like | GRB2-associated-binding protein 4 (isoform 1) | Growth factor receptor bound protein 2-associated protein 4 | GRB2-associated-binding protein 2-like | GAB2-like | GRB2 associated binding protein family member 4, transcript variant 1 | GAB4_HUMAN | GRB2-associated-binding protein 4 | GRB2-associated binder 4 | growth factor receptor bound protein 2-associated protein 4 | GRB2 associated binding protein family member 4

GAB4: A Protein Involved in Cellular Signaling and Potential Drug Targets

GAB4 (GRB2-associated binder 2-like protein) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the GABA-binding protein family, which includes other proteins such as GABA (glutamic acid-binding protein) and GABA-伪1. GAB4 is unique among these proteins because of its unique structure and its role in cellular signaling.

GAB4 is a 22-kDa protein that is composed of 118 amino acid residues. It has a unique molecular architecture that includes a catalytic active site, a transmembrane region, and a cytoplasmic tail. The transmembrane region of GAB4 is made up of four beta-strands that are held together by disulfide bonds. This region is responsible for the protein's ability to interact with other proteins and for its role in cellular signaling.

One of the unique features of GAB4 is its ability to interact with the protein GABA伪1. GABA伪1 is a critical protein that is involved in a variety of cellular signaling pathways, including the regulation of ion channels, neurotransmitter signaling, and cell survival. GAB4 and GABA伪1 have been shown to interact in a number of ways, including through direct protein-protein interactions and through direct interactions with RNA. These interactions have important implications for the regulation of cellular processes and are potential drug targets.

In addition to its role in cellular signaling, GAB4 is also a potential drug target. GAB4 has been shown to play a role in a variety of diseases, including neurodegenerative disorders, pain, and inflammation. GAB4 has also been shown to be involved in the regulation of inflammation, which suggests that it may be a useful target for the treatment of chronic inflammatory diseases.

GAB4 has also been shown to be involved in the regulation of pain. GAB4 is involved in the regulation of pain signaling, which suggests that it may be a useful target for the treatment of chronic pain. GAB4 has been shown to interact with a variety of pain receptors, including nociceptors and endogenous opioids. These interactions suggest that GAB4 may play a role in the regulation of pain signaling and that it may be a useful target for the treatment of chronic pain.

Another potential use for GAB4 as a drug target is its role in the regulation of cell survival. GAB4 has been shown to play a role in the regulation of cell survival and has been shown to be involved in a variety of cellular processes that are important for cell survival. These processes include cell growth, apoptosis, and angiogenesis. GAB4 has also been shown to interact with a variety of cell survival signaling pathways, including the TGF-β pathway. These interactions suggest that GAB4 may be a useful target for the treatment of diseases that are characterized by disruptions in cell survival, such as cancer and neurodegenerative disorders.

GAB4 is also a potential biomarker for a variety of diseases. The ability of GAB4 to interact with other proteins and to regulate cellular processes makes it a useful marker for a variety of diseases. For example, GAB4 has been shown to be involved in the regulation of cancer cell growth and has been used as a potential biomarker for cancer. GAB4 has also been shown to be involved in the regulation of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. These applications suggest that GAB4 may be a useful biomarker for a variety of neurodegenerative disorders.

In conclusion, GAB4 is a unique and important protein that is involved in a variety of cellular signaling pathways. Its ability to interact with other proteins, including GABA伪1, makes it a potential drug target and suggests that it may be a useful biomarker for a variety of diseases. Further research is needed to fully understand the role of GAB4 in cellular signaling and its potential as a drug

Protein Name: GRB2 Associated Binding Protein Family Member 4

The "GAB4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GAB4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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