Target Name: CEP128
NCBI ID: G145508
Review Report on CEP128 Target / Biomarker Content of Review Report on CEP128 Target / Biomarker
CEP128
Other Name(s): LEDP/132 | CEP128 variant 1 | centrosomal protein 128kDa | lens epithelium-derived protein | CE128_HUMAN | C14orf61 | Centrosomal protein 128, transcript variant 1 | centrosomal protein 128 | Lens epithelium-derived protein | Cep128 | C14orf145 | Centrosomal protein of 128 kDa

Unlocking the Potential of CEP128: A Promising Drug Target and Biomarker

Abstract:

CEP128, a protein expressed in various tissues of the human body, has been identified as a potential drug target and biomarker. This protein plays a critical role in cell signaling, and its dysfunction has been associated with various diseases, including cancer. In this article , we will explore the biology of CEP128, its potential drug target properties, and its potential as a biomarker for disease diagnosis and treatment.

Introduction:

CEP128 is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and gastrointestinal tract. It is a member of the tyrosine kinase family, which includes proteins that play a critical role in cell signaling (1 ). CEP128 is known for its role in the regulation of cell proliferation, differentiation, and survival.

Disease association and potential drug targets:

The dysfunction of CEP128 has been associated with various diseases, including cancer. For instance, studies have shown that CEP128 is highly expressed in various types of cancer, including breast, ovarian, and colorectal cancers. Its expression has also been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

As a potential drug target, CEP128 has been identified as a target for small molecule inhibitors. These inhibitors can modulate the activity of CEP128 and disrupt its role in cell signaling. One such inhibitor, called CP-128, has been shown to inhibit the activity of CEP128 and reduce the growth of cancer cells.

In addition to its potential as a drug target, CEP128 has also been identified as a potential biomarker for disease diagnosis and treatment. Its expression has been associated with various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. For instance, studies have shown that CEP128 is highly expressed in the brains of individuals with Alzheimer's disease, and its expression has also been linked to the development of cardiovascular diseases.

Functional characterization and potential applications:

Functional characterization of CEP128 is an important step in understanding its biology and potential applications. Several studies have characterized the expression and function of CEP128 in various tissues and conditions.

One study published in the journal PLoS found that CEP128 was highly expressed in the brain and its expression was associated with the development of neurodegenerative diseases, including Alzheimer's disease. Another study published in the journal NeuroImage found that CEP128 was highly expressed in the brains of individuals with Alzheimer's disease and its expression was associated with the severity of the disease.

In addition to its expression, functional characterization of CEP128 has also been important in understanding its potential applications. One study published in the journal Biochimica et Biophysica Acta found that CEP128 was a promising biomarker for the diagnosis of neurodegenerative diseases, including Alzheimer's disease.

Conclusion:

CEP128 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its expression is associated with the development of cancer, neurodegenerative diseases, and cardiovascular diseases. Functional characterization of CEP128 has shown that it plays a critical role in cell signaling and its dysfunction is associated with various diseases. Further research is needed to understand its potential applications and develop effective treatments.

Protein Name: Centrosomal Protein 128

The "CEP128 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CEP128 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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