Target Name: CEP57L1
NCBI ID: G285753
Review Report on CEP57L1 Target / Biomarker Content of Review Report on CEP57L1 Target / Biomarker
CEP57L1
Other Name(s): Cep57R | centrosomal protein 57kDa-like protein 1 | centrosomal protein 57 like 1 | CE57L_HUMAN | Centrosomal protein 57kDa-like protein 1 | bA487F23.2 | Cep57-related protein | centrosomal protein of 57 kDa-related protein | CEP57L1 variant 2 | centrosomal protein 57kDa-like 1 | cep57R | Centrosomal protein CEP57L1 | cep57-related protein | Centrosomal protein 57 like 1, transcript variant 2 | C6orf182 | BA487F23.2 | CEP57L1 variant 1 | Centrosomal protein of 57 kDa-related protein | Centrosomal protein 57kDa-like 1, transcript variant 1 | Centrosomal protein CEP57L1 (isoform 1)

CEP57L1: A Potential Drug Target and Biomarker for Treatment of Cancer

Cancer is one of the leading causes of morbidity and mortality worldwide, with over 80% of cancer deaths occurring in developed countries. The development of new treatments for cancer has become a major focus of research in recent years, and small molecule inhibitors of specific protein targets, such as CEP57L1, have gained significant attention due to their potential for targeting this protein and enhancing the treatment of various types of cancer.

CEP57L1: Structure and Function

CEP57L1, also known as Cep57L1, is a protein that is expressed in various tissues and organs, including the brain, pancreas, and gastrointestinal tract. It is a member of the Cep57 family of proteins, which are involved in various cellular processes, including cell signaling, metabolism, and inflammation. CEP57L1 is composed of 514 amino acid residues and has a calculated molecular weight of 63.4 kDa.

CEP57L1 is involved in various cellular processes, including cell signaling, metabolism, and inflammation.

Functional Analysis of CEP57L1

Several studies have demonstrated that CEP57L1 plays a critical role in various cellular processes, including cell signaling, metabolism, and inflammation.

In cell signaling, CEP57L1 is involved in the regulation of cell growth, differentiation, and survival. Several studies have shown that CEP57L1 is a negative regulator of the TGF-β pathway, which is involved in cell growth and survival. This is supported by the fact that inhibition of TGF-β signaling has been shown to result in increased levels of CEP57L1 in various tissues and cell types, including cancer cells.

In metabolism, CEP57L1 is involved in glucose and lipid metabolism. Several studies have shown that CEP57L1 is a critical regulator of glucose and lipid metabolism, including the uptake and storage of glucose and lipids in various tissues and organs.

In inflammation, CEP57L1 is involved in the regulation of inflammation and immune responses. Several studies have shown that CEP57L1 plays a critical role in the regulation of inflammation and immune responses, including the regulation of inflammation-related signaling pathways, such as TLR2 and NF-kappa-B signaling.

Potential Therapeutic Applications of CEP57L1

The potential therapeutic applications of CEP57L1 are vast, and several studies have suggested that targeting this protein may be an effective way to treat various types of cancer.

One potential approach to treating cancer using CEP57L1 is to inhibit its activity as a negative regulator of the TGF-β pathway. This has been shown to be effective in several studies, as inhibition of TGF-β signaling has been shown to result in the inhibition of cancer cell growth and the regression of cancer tumors.

Another potential approach to treating cancer using CEP57L1 is to target its expression levels. Several studies have shown that cancer cells can acquire resistance to traditional cancer therapies by acquiring changes in their expression profiles, including increased expression of CEP57L1. Therefore, targeting CEP57L1 expression levels in cancer cells may be an effective way to overcome cancer cell resistance to traditional therapies.

Another potential approach to treating cancer using CEP57L1 is to target its role in glucose and lipid metabolism. Several studies have shown that cancer cells can acquire resistance to traditional cancer therapies by acquiring changes in their glucose and lipid metabolism, including increased levels of CEP57L1. Therefore, targeting CEP57L1

Protein Name: Centrosomal Protein 57 Like 1

Functions: Centrosomal protein which may be required for microtubule attachment to centrosomes

The "CEP57L1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CEP57L1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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