Target Name: CFAP298
NCBI ID: G56683
Review Report on CFAP298 Target / Biomarker Content of Review Report on CFAP298 Target / Biomarker
CFAP298
Other Name(s): Cilia- and flagella-associated protein 298 (isoform 1) | CF298_HUMAN | Cilia and flagella associated protein 298, transcript variant 1 | CILD26 | Cilia- and flagella-associated protein 298 | C21orf48 | CFAP298 variant 1 | protein kurly homolog | DNAAF16 | dynein axonemal assembly factor 16 | FBB18 | UPF0769 protein C21orf59 | cilia and flagella associated protein 298 | prostate cancer upregulated protein 1 | Protein kurly homolog | Kur | C21orf59 | kurly homolog | uncharacterized protein C21orf59

CFAP298: Cilia and Flagella Regulator and Potential Drug Target

Cilia- and flagella-associated protein 298 (CFAP298), also known as isoform 1, is a protein that plays a crucial role in the function of cilia and flagella, which are small structures found in the cells of many organisms. Cilia and flagella are responsible for the movement and transport of particles and molecules across the cell membrane, and are essential for the proper functioning of many cellular processes.

CFAP298 is a member of the CFAP family, which includes a variety of proteins that share similar structures and functions. This family of proteins is involved in a wide range of cellular processes, including the regulation of cell growth, differentiation, and survival.

One of the key functions of CFAP298 is its role in the regulation of cilia and flagella structure and function. Cilia and flagella are small structures that are composed of a single layer of protein molecules, which are held in place by a hydrophobic interaction. CFAP298 helps to maintain the stability of these structures by interacting with and helping to modify the proteins that make up the cilia and flagella.

CFAP298 is also involved in the regulation of the movement of cilia and flagella. These structures are able to move along the cell membrane in a specific direction, which is determined by the orientation of the proteins that make up the cilia and flagella. CFAP298 helps to regulate the movement of these structures by interacting with the proteins that make up the cilia and flagella and by contributing to the overall stability of the structures.

In addition to its role in the regulation of cilia and flagella structure and function, CFAP298 is also involved in the regulation of many other cellular processes. For example, it has been shown to be involved in the regulation of cell growth, differentiation, and survival. , as well as the regulation of cell-cell interactions and the development of cancer.

CFAP298 is also a potential drug target for several diseases. For example, studies have shown that it is involved in the development and progression of various cancers, including breast, ovarian, and prostate cancer. Additionally, CFAP298 has also been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

CFAP298 is also a potential biomarker for several diseases. For example, studies have shown that it is involved in the diagnosis of various diseases, including cancer, neurodegenerative diseases, and respiratory diseases. Additionally, CFAP298 has been shown to be a potential target for several diseases. drugs that are currently being developed for these diseases, including cancer therapies and neurodegenerative treatments.

In conclusion, CFAP298 is a protein that plays a crucial role in the function of cilia and flagella, and is involved in a wide range of cellular processes. It is a potential drug target for several diseases and could be used as a biomarker for the diagnosis and treatment of these diseases. Further research is needed to fully understand the role of CFAP298 in cellular processes and its potential as a drug target.

Protein Name: Cilia And Flagella Associated Protein 298

Functions: Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity)

The "CFAP298 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CFAP298 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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