CERKL: A Protein Implicated in Stem Cell and Cell Death Regulation

Target Name: CERKL

NCBI ID: G375298

CERKL

CERKL: A Protein Implicated in Stem Cell and Cell Death Regulation

CERKL (CERKL_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including neurodegenerative disorders, autoimmune diseases, and cancer.

One of the defining features of CERKL is its role in the regulation of stem cell proliferation. CERKL has been shown to play a critical role in the self-renewal of stem cells, which are the cells that give rise to all tissues of the body. Specifically, CERKL is involved in the regulation of the stem cell marker PDGFR-尾, which is a key factor in the self-renewal of stem cells.

In addition to its role in stem cell proliferation, CERKL is also involved in the regulation of cell death. Studies have shown that CERKL has been shown to play a role in the regulation of cell death, particularly in the context of neurodegenerative disorders. For example, studies have shown that CERKL is involved in the regulation of the neurotoxin 尾-amyloid, which is thought to contribute to the development of Alzheimer's disease.

CERKL is also involved in the regulation of inflammation, and has been shown to play a role in the development of autoimmune diseases. For example, studies have shown that CERKL is involved in the regulation of the immune response, and that it is involved in the development of autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

In addition to its involvement in stem cell proliferation and regulation of cell death, CERKL is also involved in the regulation of inflammation. Studies have shown that CERKL is involved in the regulation of the immune response, and that it is involved in the development of autoimmune diseases.

CERKL has also been shown to play a role in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and inflammation, and is thought to be involved in the development of many diseases, including cancer.

In conclusion, CERKL is a protein that is involved in a number of important biological processes in the human body. Its role in stem cell proliferation and regulation of cell death, as well as its involvement in the regulation of inflammation and cell signaling pathways, makes CERKL a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of CERKL in these processes, and to develop effective therapies for the treatment of diseases associated with its dysfunction.

Protein Name: Ceramide Kinase Like

Functions: Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis in oxidative stress conditions

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