Adenosine deaminase (nonspecified subtype) Related Diseases

Adenosine deaminase (nonspecified subtype)

Related Diseases

1) Arthritis
Arthritis, also known as inflammatory joint disease, is related to rheumatoid arthritis and juvenile rheumatoid arthritis, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Arthritis is SYK (Spleen Associated Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Entecavir and Chlorhexidine have been mentioned in the context of this disorder. Affiliated tissues include joint, bone and bone marrow, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and homeostasis/metabolism

2) Inborn Errors Of Metabolism
Inherited Metabolic Disorder, also known as inborn errors of metabolism, is related to phenylketonuria and carbohydrate metabolic disorder. An important gene associated with Inherited Metabolic Disorder is TKFC (Triokinase And FMN Cyclase), and among its related pathways/superpathways are Cell differentiation - expanded index and Interactions between immune cells and microRNAs in tumor microenvironment. The drugs Bezafibrate and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, liver and t cells.

3) Metabolic Diseases
3-Hydroxyacyl-Coa Dehydrogenase Deficiency, also known as hadh deficiency, is related to long-chain 3-hydroxyacyl-coa dehydrogenase deficiency and hyperinsulinemic hypoglycemia, familial, 4, and has symptoms including emaciation An important gene associated with 3-Hydroxyacyl-Coa Dehydrogenase Deficiency is HADH (Hydroxyacyl-CoA Dehydrogenase). The drugs Naloxone and Buprenorphine have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and skeletal muscle, and related phenotypes are feeding difficulties in infancy and growth delay

4) Stroke, Ischemic
Stroke, Ischemic, also known as cerebral infarction, is related to sneddon syndrome and brain small vessel disease 1, and has symptoms including angina pectoris, back pain and chest pain. An important gene associated with Stroke, Ischemic is F5 (Coagulation Factor V), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Heparin, bovine and Nadroparin have been mentioned in the context of this disorder. Affiliated tissues include Bone and Brain, and related phenotypes are stroke and homeostasis/metabolism

5) Waldenstrom Macroglobulinemia
Lymphoplasmacytic Lymphoma, also known as waldenström macroglobulinaemia without mention of remission, is related to macroglobulinemia and waldenstroem's macroglobulinemia. An important gene associated with Lymphoplasmacytic Lymphoma is PAX5 (Paired Box 5), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Thalidomide and Chlorambucil have been mentioned in the context of this disorder. Affiliated tissues include b cells, bone marrow and t cells, and related phenotypes are homeostasis/metabolism and cellular

6) Multiple Sclerosis
Multiple Sclerosis, also known as ms, is related to pediatric multiple sclerosis and autoimmune hepatitis, and has symptoms including back pain, headache and hemiplegia. An important gene associated with Multiple Sclerosis is HLA-DRB1 (Major Histocompatibility Complex, Class II, DR Beta 1), and among its related pathways/superpathways are Phosphorylation of CD3 and TCR zeta chains and Cell differentiation - expanded index. The drugs Acetaminophen and Promethazine have been mentioned in the context of this disorder. Affiliated tissues include Neural Tube and Limb, and related phenotypes are spasticity and diplopia

7) Multiple Sclerosis, Relapsing-remitting
Relapsing-Remitting Multiple Sclerosis, also known as relapsing-remitting ms, is related to secondary progressive multiple sclerosis and multiple sclerosis. An important gene associated with Relapsing-Remitting Multiple Sclerosis is TUG1 (Taurine Up-Regulated 1), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Alemtuzumab and Phylloquinone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone marrow, and related phenotypes are growth/size/body region and homeostasis/metabolism

8) Multiple Sclerosis, Secondary Progressive
Secondary Progressive Multiple Sclerosis, also known as multiple sclerosis, secondary progressive, is related to relapsing-remitting multiple sclerosis and multiple sclerosis. An important gene associated with Secondary Progressive Multiple Sclerosis is MBP (Myelin Basic Protein), and among its related pathways/superpathways are superpathway of L-citrulline metabolism and Amino acid metabolism. The drugs Dalfampridine and Cladribine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, brain and spinal cord, and related phenotypes are immune system and hematopoietic system

9) Angina Pectoris
Angina Pectoris, also known as prinzmetal's variant angina, is related to polycythemia vera and intermittent claudication, and has symptoms including other and unspecified angina pectoris An important gene associated with Angina Pectoris is EDN1 (Endothelin 1), and among its related pathways/superpathways are Signal Transduction and Response to elevated platelet cytosolic Ca2+. The drugs Candesartan cilexetil and Amiodarone have been mentioned in the context of this disorder. Affiliated tissues include heart, smooth muscle and bone marrow, and related phenotypes are homeostasis/metabolism and muscle

10) Acute Lymphocytic Leukemia
Leukemia, Acute Lymphoblastic, also known as acute lymphoblastic leukemia, is related to b-lymphoblastic leukemia/lymphoma and hematologic cancer, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia, Acute Lymphoblastic is PAX5 (Paired Box 5), and among its related pathways/superpathways are Cell differentiation - expanded index and miRNAs involvement in the immune response in sepsis. The drugs Epirubicin and Nicotine have been mentioned in the context of this disorder. Affiliated tissues include Blood, and related phenotype is acute lymphoblastic leukemia.

11) Chronic Lymphocytic Leukemia
Leukemia, Chronic Lymphocytic 2, also known as leukemia, chronic lymphocytic, susceptibility to, 2, is related to chronic lymphocytic leukemia/small lymphocytic lymphoma and chromosomal triplication, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia, Chronic Lymphocytic 2 is CLLS2 (Disrupted In B-Cell Neoplasia), and among its related pathways/superpathways are Hematopoietic Stem Cells and Lineage-specific Markers and Interleukin-4 and Interleukin-13 signaling. The drugs Valganciclovir and Chlorambucil have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and b cells, and related phenotypes are chronic lymphatic leukemia and immune system

12) Hairy Cell Leukemia
Classic Hairy Cell Leukemia, also known as leukemic reticuloendotheliosis, is related to intrapelvic lymph node leukemic reticuloendotheliosis and reticuloendotheliosis, x-linked. An important gene associated with Classic Hairy Cell Leukemia is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase). The drugs Cladribine and 2-chloro-3'-deoxyadenosine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spleen and bone.

13) Lymphoma
Lymphosarcoma, also known as lymphoma, diffuse, is related to lymphoma, non-hodgkin, familial and lymphoma, hodgkin, classic. An important gene associated with Lymphosarcoma is BCL6 (BCL6 Transcription Repressor), and among its related pathways/superpathways are Direct p53 effectors and Interleukin-4 and Interleukin-13 signaling. The drugs Crofelemer and Aprepitant have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and myeloid.

14) Lymphoma, Mantle Cell
Mantle Cell Lymphoma, also known as malignant lymphoma, lymphocytic, intermediate differentiation, diffuse, is related to lymphoma and burkitt lymphoma. An important gene associated with Mantle Cell Lymphoma is ATM (ATM Serine/Threonine Kinase), and among its related pathways/superpathways are Cellular responses to stimuli and Prolactin Signaling. The drugs Cyclophosphamide and Cytarabine have been mentioned in the context of this disorder. Affiliated tissues include b cells, lymph node and t cells, and related phenotypes are lymphadenopathy and b-cell lymphoma

15) Lymphoma, B-cell
B-Cell Lymphoma, also known as lymphoma, b-cell, is related to marginal zone b-cell lymphoma and lymphoma, mucosa-associated lymphoid type. An important gene associated with B-Cell Lymphoma is MIR17 (MicroRNA 17), and among its related pathways/superpathways are Cytokine Signaling in Immune system and NF-kappaB Signaling. The drugs Lomustine and Rivoceranib have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and bone marrow, and related phenotypes are endocrine/exocrine gland and cellular

16) Lymphoma, Follicular
Follicular Lymphoma, also known as lymphoma, follicular, is related to lymphoma and burkitt lymphoma. An important gene associated with Follicular Lymphoma is BCL10 (BCL10 Immune Signaling Adaptor), and among its related pathways/superpathways are Interleukin-4 and Interleukin-13 signaling and DNA damage response (only ATM dependent). The drugs Protective Agents and Neuroprotective Agents have been mentioned in the context of this disorder. Affiliated tissues include b cells, t cells and bone marrow, and related phenotypes are fever and lymphoma

17) Inflammatory Bowel Disease
Inflammatory Bowel Disease, also known as inflammatory bowel diseases, is related to inflammatory bowel disease 6 and inflammatory bowel disease 9. An important gene associated with Inflammatory Bowel Disease is IL37 (Interleukin 37). The drugs Copper and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and bone marrow.

18) Pain
Paine Syndrome, also known as pain disorder, is related to paroxysmal extreme pain disorder and indifference to pain, congenital, autosomal recessive. An important gene associated with Paine Syndrome is HFE (Homeostatic Iron Regulator), and among its related pathways/superpathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. The drugs Pregabalin and Dinoprostone have been mentioned in the context of this disorder. Affiliated tissues include dorsal root ganglion, spinal cord and breast, and related phenotypes are microcephaly and spastic diplegia

19) Leukemia
Leukemia, also known as leukaemia, unspecified, without mention of remission, is related to myeloid leukemia and leukemia, chronic myeloid, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia is MIR27A (MicroRNA 27a), and among its related pathways/superpathways are NF-kappaB Signaling and Imatinib and chronic myeloid leukemia. The drugs Azacitidine and Decitabine have been mentioned in the context of this disorder. Affiliated tissues include myeloid, bone marrow and t cells, and related phenotypes are Increased HDAC inhibitor resistance and endocrine/exocrine gland

20) Graft-versus-host Disease
Graft-Versus-Host Disease, also known as graft-versus-host disease, susceptibility to, is related to bronchiolitis obliterans and acute graft versus host disease. An important gene associated with Graft-Versus-Host Disease is IL10 (Interleukin 10), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Tacrolimus and Lomustine have been mentioned in the context of this disorder. Affiliated tissues include Bone, bone marrow and t cells, and related phenotypes are elevated hepatic transaminase and skin erosion

21) Systemic Mastocytosis
Systemic Mastocytosis, also known as systemic mast cell disease, is related to systemic mastocytosis with associated hematologic neoplasm and indolent systemic mastocytosis. An important gene associated with Systemic Mastocytosis is KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Protein Kinase Inhibitors and Imatinib Mesylate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and spleen, and related phenotypes are Decreased viability and Decreased viability

22) Adenosine Deaminase Deficiency
Adenosine Deaminase Deficiency, also known as ada deficiency, is related to severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency and severe combined immunodeficiency, x-linked. An important gene associated with Adenosine Deaminase Deficiency is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Metabolism of nucleotides. The drugs Busulfan and Antineoplastic Agents, Alkylating have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and lymph node, and related phenotypes are failure to thrive and sinusitis

23) Autoimmune Disease
Autoimmune Disease, also known as autoimmune diseases, is related to vitiligo-associated multiple autoimmune disease susceptibility 1 and systemic lupus erythematosus. An important gene associated with Autoimmune Disease is AIS4 (Autoimmune Disease, Susceptibility To, 4), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Sofosbuvir and Ledipasvir have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and skin, and related phenotypes are autoimmune antibody positivity and endocrine/exocrine gland

24) Vasculitis
Vasculitis, also known as autoimmune vasculitis, is related to hypersensitivity vasculitis and churg-strauss syndrome, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Vasculitis is PRTN3 (Proteinase 3), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Innate Immune System. The drugs Cyclophosphamide and Alemtuzumab have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, lung and heart, and related phenotypes are immune system and hematopoietic system

25) Neuromyelitis Optica
Neuromyelitis Optica, also known as devic syndrome, is related to transverse myelitis and neuritis. An important gene associated with Neuromyelitis Optica is AQP4 (Aquaporin 4), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Antineoplastic Agents, Immunological and Daratumumab have been mentioned in the context of this disorder. Affiliated tissues include Umbilical Cord, spinal cord and eye, and related phenotypes are optic neuritis and visual loss

26) Myasthenia Gravis
Myasthenia Gravis, also known as mg, is related to neonatal myasthenia gravis and myasthenic syndrome, congenital, 6, presynaptic, and has symptoms including ptosis, diplopia and dysphagia. An important gene associated with Myasthenia Gravis is AKAP12 (A-Kinase Anchoring Protein 12), and among its related pathways/superpathways are Overview of interferons-mediated signaling pathway and NF-kappaB Signaling. The drugs Salbutamol and Eculizumab have been mentioned in the context of this disorder. Affiliated tissues include thymus, eye and skeletal muscle, and related phenotypes are ptosis and diplopia

27) Non-Hodgkin Lymphoma
Lymphoma, also known as non-hodgkin malignant lymphoma nos, is related to lymphoma, hodgkin, classic and lymphoma, non-hodgkin, familial. An important gene associated with Lymphoma is PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11), and among its related pathways/superpathways are IL-9 Signaling Pathways and NF-kappaB Signaling. The drugs Ferrous succinate and Posaconazole have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and myeloid, and related phenotypes are immune system and hematopoietic system

28) Hyperuricemia
Hyperuricemia, also known as blood urate raized, is related to hyperuricemia, hprt-related and tubulointerstitial kidney disease, autosomal dominant, 1, and has symptoms including cachexia, cyanosis and dyspnea. An important gene associated with Hyperuricemia is UMOD (Uromodulin), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Levoleucovorin and Mecobalamin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and liver, and related phenotypes are renal/urinary system and homeostasis/metabolism

29) Hypertension
Hypertension, Essential, also known as essential hypertension, is related to pulmonary hypertension and renovascular hypertension, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Hypertension, Essential is PTGIS (Prostaglandin I2 Synthase), and among its related pathways/superpathways are Development Angiotensin activation of ERK and "Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics". The drugs Digoxin and Warfarin have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and eye, and related phenotypes are elevated systolic blood pressure and elevated diastolic blood pressure

The "Adenosine deaminase (nonspecified subtype) Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Adenosine deaminase (nonspecified subtype) comprehensively including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Disease Target / Biomarker

<< Back