Glutathione peroxidase (nonspecified subtype) Related Diseases

Glutathione peroxidase (nonspecified subtype)

Related Diseases

1) Arthritis
Arthritis, also known as inflammatory joint disease, is related to rheumatoid arthritis and juvenile rheumatoid arthritis, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Arthritis is SYK (Spleen Associated Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Entecavir and Chlorhexidine have been mentioned in the context of this disorder. Affiliated tissues include joint, bone and bone marrow, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and homeostasis/metabolism

2) Stroke
Cerebrovascular Disease, also known as cerebrovascular disorder, is related to basal ganglia cerebrovascular disease and stroke, ischemic, and has symptoms including headache, transient ischemic attacks, stereotypic symptoms and angina pectoris. An important gene associated with Cerebrovascular Disease is HOTAIR (HOX Transcript Antisense RNA), and among its related pathways/superpathways are Signal Transduction and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Acetylcarnitine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and heart, and related phenotypes are homeostasis/metabolism and growth/size/body region

3) Coronary Artery Disease
Coronary Heart Disease 1, also known as coronary heart disease, is related to angina pectoris and abdominal obesity-metabolic syndrome 1, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Coronary Heart Disease 1 is CX3CR1 (C-X3-C Motif Chemokine Receptor 1), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Simvastatin and Lovastatin have been mentioned in the context of this disorder. Affiliated tissues include Limb and Bone, and related phenotypes are Increased free cholesterol and Increased LDL uptake

4) Atherosclerosis
Atherosclerosis Susceptibility, also known as atherosclerosis, is related to cerebral atherosclerosis and generalized atherosclerosis, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Atherosclerosis Susceptibility is ATHS (Atherosclerosis Susceptibility (Lipoprotein Associated)), and among its related pathways/superpathways are "Plasma lipoprotein assembly, remodeling, and clearance" and Interleukin-4 and Interleukin-13 signaling. The drugs Enalaprilat and Enalapril have been mentioned in the context of this disorder. Affiliated tissues include Heart, and related phenotypes are hypertriglyceridemia and myocardial infarction

5) Asthma
Asthma, also known as chronic obstructive asthma, is related to allergic asthma and childhood-onset asthma, and has symptoms including recurring periods of wheezing, chest tightness and shortness of breath. An important gene associated with Asthma is IL13 (Interleukin 13), and among its related pathways/superpathways are Allograft rejection and Interleukin-4 and Interleukin-13 signaling. The drugs Fentanyl and Etomidate have been mentioned in the context of this disorder. Affiliated tissues include Lung, smooth muscle and skin, and related phenotypes are asthma and bronchoconstriction

6) Myocardial Infarction
Myocardial Infarction, also known as heart attack, is related to lipoprotein quantitative trait locus and cardiovascular system disease, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Myocardial Infarction is MIAT (Myocardial Infarction Associated Transcript), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include Bone and Limb.

7) Heart Failure
Congestive Heart Failure, also known as congestive heart disease, is related to cardiomyopathy, dilated, 1e and orthostatic intolerance, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Congestive Heart Failure is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are Cardiac conduction and "Antiarrhythmic Pathway, Pharmacodynamics". The drugs Salbutamol and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Lateral Plate Mesoderm, and related phenotypes are muscle and homeostasis/metabolism

8) Meniere's Disease
Meniere Disease, also known as meniere's disease, is related to otosclerosis and inner ear disease, and has symptoms including coughing, snoring and tinnitus. An important gene associated with Meniere Disease is FAM136A (Family With Sequence Similarity 136 Member A). The drugs Tocopherol and Nicotinamide have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and adrenal cortex, and related phenotypes are hearing impairment and vertigo

9) Ulcerative Colitis
Inflammatory Bowel Disease 1, also known as inflammatory bowel disease 1, is related to inflammatory bowel disease 19 and inflammatory bowel disease 17, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Inflammatory Bowel Disease 1 is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Magnesium citrate and Prucalopride have been mentioned in the context of this disorder. Affiliated tissues include colon, bone marrow and bone, and related phenotypes are growth delay and abdominal pain

10) Inflammatory Bowel Disease
Inflammatory Bowel Disease, also known as inflammatory bowel diseases, is related to inflammatory bowel disease 6 and inflammatory bowel disease 9. An important gene associated with Inflammatory Bowel Disease is IL37 (Interleukin 37). The drugs Copper and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and bone marrow.

11) Cataract
Cataract, also known as cataracts, is related to senile cataract and cataract 1, multiple types. An important gene associated with Cataract is CRYBB3 (Crystallin Beta B3), and among its related pathways/superpathways is 1q21.1 copy number variation syndrome. The drugs Cyclopentolate and Atropine have been mentioned in the context of this disorder. Affiliated tissues include Eye, endothelial and cortex, and related phenotype is vision/eye.

12) Leukemia
Leukemia, also known as leukaemia, unspecified, without mention of remission, is related to myeloid leukemia and leukemia, chronic myeloid, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia is MIR27A (MicroRNA 27a), and among its related pathways/superpathways are NF-kappaB Signaling and Imatinib and chronic myeloid leukemia. The drugs Azacitidine and Decitabine have been mentioned in the context of this disorder. Affiliated tissues include myeloid, bone marrow and t cells, and related phenotypes are Increased HDAC inhibitor resistance and endocrine/exocrine gland

13) Rheumatoid Arthritis
Rheumatoid Arthritis, also known as ra, is related to arthritis and psoriatic arthritis, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Rheumatoid Arthritis is PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22), and among its related pathways/superpathways are NF-kappaB Signaling and Genes associated with the development of rheumatoid arthritis. The drugs Entecavir and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include Cartilage, joint and bone, and related phenotypes are joint stiffness and fatigue

14) Diabetes
Diabetes Mellitus, also known as diabetes, is related to type 2 diabetes mellitus and gestational diabetes, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Diabetes Mellitus is KCNJ11 (Potassium Inwardly Rectifying Channel Subfamily J Member 11), and among its related pathways/superpathways are Regulation of beta-cell development and Cell differentiation - expanded index. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, bone marrow and kidney.

15) Diabetic Neuropathy
Diabetic Neuropathy, also known as diabetic neuropathies, is related to microvascular complications of diabetes 3 and diabetic polyneuropathy, and has symptoms including neuralgia and sciatica. An important gene associated with Diabetic Neuropathy is AKR1B1 (Aldo-Keto Reductase Family 1 Member B), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and CREB Pathway. The drugs Histamine and Cetirizine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone marrow and dorsal root ganglion, and related phenotypes are no effect and no effect

16) Diabetic Nephropathy
Microvascular Complications of Diabetes 2, also known as microvascular complications of diabetes, susceptibility to, 2, is related to microvascular complications of diabetes 3 and background diabetic retinopathy. An important gene associated with Microvascular Complications of Diabetes 2 is EPO (Erythropoietin). The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include kidney, endothelial and retina.

17) Retinopathy, Diabetic
Microvascular Complications of Diabetes 5, also known as diabetic retinopathy, is related to microvascular complications of diabetes 1 and type 1 diabetes mellitus. An important gene associated with Microvascular Complications of Diabetes 5 is PON1 (Paraoxonase 1), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include Eye, and related phenotypes are homeostasis/metabolism and cardiovascular system

18) Bipolar Disorder
Bipolar Disorder, also known as depression, bipolar, is related to bipolar i disorder and schizophrenia. An important gene associated with Bipolar Disorder is MAFD1 (Major Affective Disorder 1), and among its related pathways/superpathways are Neurotransmitter clearance and "Methylphenidate Pathway, Pharmacodynamics". The drugs Coal tar and Eleuthero have been mentioned in the context of this disorder. Affiliated tissues include brain, prefrontal cortex and eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

19) Psoriasis
Psoriasis is related to psoriasis 7 and psoriasis 10, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis is MIR203A (MicroRNA 203a), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Metformin and Vedolizumab have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and endothelial.

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