Study on GSTZ1 (MAAID): Potential Drug Target and Biomarker for Various Diseases

Target Name: GSTZ1

NCBI ID: G2954

GSTZ1

Study on GSTZ1 (MAAID): Potential Drug Target and Biomarker for Various Diseases

GSTZ1 (MAAID), a gene located on chromosome 6, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its function and significance have been studied extensively in the scientific literature, and its potential as a drug target continue to grow.

GSTZ1 is a gene that encodes a protein known as GSTZ1 (MAAID). GSTZ1 is a member of the GST family of transmembrane proteins, which are involved in the detoxification of xenobiotics and other harmful substances. The MAAID protein is a variant of the GSTZ gene that has been shown to have unique functions in various cellular processes.

One of the most significant functions of GSTZ1 is its role in the detoxification of harmful substances. GSTZ1 is expressed in many different tissues and cells in the body, including the liver, spleen, and intestine. It is responsible for carrying out the detoxification of a wide variety of compounds, including drugs, toxins, and other harmful substances that enter the body. This function is critical for maintaining the health and integrity of the body's tissues and systems.

In addition to its role in detoxification, GSTZ1 is also involved in the regulation of cellular processes that are essential for proper development and function. For example, GSTZ1 has been shown to play a role in the development and maintenance of neuronal connectivity in the brain, as well as in the regulation of ion channels and neurotransmitter release.

GSTZ1 has also been shown to be involved in the regulation of cellular processes that are important for cancer progression. For example, studies have shown that GSTZ1 is highly expressed in various types of cancer, and that it is involved in the development and progression of these diseases. This suggests that targeting GSTZ1 with drugs or other therapeutic agents may be an effective way to treat cancer.

Another potential function of GSTZ1 is its role as a biomarker for various diseases. GSTZ1 has been shown to be involved in the regulation of cellular processes that are important for the development and progression of a wide variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that GSTZ1 is involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

In addition to its potential as a drug target and biomarker, GSTZ1 is also of interest from a fundamental biological perspective. The GSTZ gene is part of a larger family of transmembrane proteins that are involved in a variety of cellular processes. By studying the function of GSTZ1, researchers have gained new insights into the mechanisms of cellular detoxification and regulation, as well as the regulation of various diseases.

Overall, GSTZ1 (MAAID) is a gene that has significant potential as a drug target and biomarker for a wide variety of diseases. Its functions in detoxification, regulation of cellular processes, and cancer progression make it an attractive target for therapeutic agents that can be used to treat a range of diseases. Further research is needed to fully understand the role of GSTZ1 in these processes, as well as its potential as a drug and biomarker.

Protein Name: Glutathione S-transferase Zeta 1

Functions: Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid

The "GSTZ1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTZ1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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