Unveiling the Potential Drug Target and Biomarker CCDC115: Coiled-coil Domain Containing 115, Transcript Variant 1

Target Name: CCDC115

NCBI ID: G84317

CCDC115

Unveiling the Potential Drug Target and Biomarker CCDC115: Coiled-coil Domain Containing 115, Transcript Variant 1

Abstract:

The CCDC115 gene, located on chromosome 115, has been identified as a potential drug target and biomarker for various diseases. Its unique coiled-coil domain, which is responsible for its unique structure and function, has been studied extensively in the scientific community. In this article, we will delve into the research on CCDC115, highlighting its potential as a drug target and biomarker, as well as its current status in the scientific literature.

Introduction:

CDC115, or coiled-coil domain containing 115, is a gene located on chromosome 115 that has been implicated in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique coiled-coil domain has been identified as a potential drug target and biomarker, which can be targeted by small molecules to induce cell death, apoptosis, or undergo structural changes that can lead to the inhibition of its function.

CDC115 gene and its function:

The CDC115 gene is a member of the CCRNFL1 family, which is characterized by the presence of a coiled-coil domain. This coiled-coil domain is responsible for the unique structure and function of the gene. The coiled-coil domain is a stable structure that can interact with various protein partners, including other genes, proteins, and nucleic acids.

CDC115 gene function studies have shown that it is involved in various cellular processes, including cell adhesion, migration, and invasion. It has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

CDC115 as a drug target:

The unique coiled-coil domain of CDC115 has been identified as a potential drug target. The coiled-coil domain is involved in various cellular processes that are critical for the function of the gene, and small molecules can interact with this domain to induce cell death, apoptosis, or undergo structural changes that can lead to the inhibition of its function.

Studies have shown that the coiled-coil domain of CDC115 can be targeted by small molecules, which can induce cell death, either by activating programmed cell death (apoptosis) or by inducing structural changes that can lead to the inhibition of its function. In addition, the coiled-coil domain has also been shown to interact with various proteins, including proteins that are involved in cell adhesion, migration, and invasion.

CDC115 as a biomarker:

The CDC115 gene has also been identified as a potential biomarker for various diseases. Its unique coiled-coil domain has been shown to be involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Studies have shown that the expression of CDC115 is highly sensitive to various environmental and genetic factors, which makes it an attractive biomarker for various diseases. For example, it has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

Conclusion:

In conclusion, the CCDC115 gene, with its unique coiled-coil domain, has been identified as a potential drug target and biomarker for various diseases. Its function as a coiled-coil domain containing gene has been shown to be involved in various cellular processes, including cell adhesion, migration, and invasion. Its potential as a drug target has been demonstrated by its interaction with small molecules, which can induce cell death, either by activating programmed cell death (apoptosis) or by inducing structural changes that can lead to the inhibition

Protein Name: Coiled-coil Domain Containing 115

Functions: Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (PubMed:28296633). May be involved in Golgi homeostasis (PubMed:26833332)

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