Study on The Role of CACNA1H in Muscle Contractions and Other Physiological Processes

Target Name: CACNA1H

NCBI ID: G8912

CACNA1H

Other Name(s): CAC1H_HUMAN | Voltage-gated calcium channel subunit alpha Cav3.2 | Voltage-gated calcium channel alpha subunit CavT.2 | HALD4 | voltage dependent t-type calcium channel alpha-1H subunit | Cav3.2 | Voltage-dependent T-type calcium channel subunit alpha-1H | calcium voltage-gated channel subunit alpha1 H | Calcium channel, voltage-dependent, T type, alpha 1Hb subunit | Voltage-dependent T-type calcium channel subunit alpha-1H (isoform a) | calcium channel, voltage-dependent, T type, alpha 1H subunit | CACNA1H variant 2 | EIG6 | Calcium voltage-gated channel subunit alpha1 H, transcript variant 1 | calcium channel, voltage-dependent, T type, alpha 1Hb subunit | Voltage-dependent T-type calcium channel subunit alpha-1H (isoform b) | Voltage-gated calcium channel alpha subunit Cav3.2 | voltage-gated calcium channel alpha subunit Cav3.2 | low-voltage-activated calcium channel alpha1 3.2 subunit | ECA6 | voltage-gated calcium channel subunit alpha Cav3.2 | CACNA1HB | low-voltage-activated calcium channel alpha13.2 subunit | voltage-gated calcium channel alpha subunit CavT.2 | Low-voltage-activated calcium channel alpha1 3.2 subunit | CACNA1H variant 1 | Calcium voltage-gated channel subunit alpha1 H, transcript variant 2 | Low-voltage-activated calcium channel alpha13.2 subunit

Study on The Role of CACNA1H in Muscle Contractions and Other Physiological Processes

CACNA1H, also known as CAC1H-HUMAN, is a protein that is expressed in many different tissues throughout the body. It is a member of the calcium-dependent chloride channels (CACNA) family, which are involved in the regulation of intracellular calcium levels.

One of the key functions of CACNA1H is its role in the regulation of muscle contractions. It is a protein that is expressed in the muscle fibers and plays a role in the regulation of the contractions that occur during muscle growth and development.

In addition to its role in muscle contractions, CACNA1H is also involved in the regulation of other physiological processes that are important for the proper functioning of the body. For example, it is involved in the regulation of the release of hormones from the pituitary gland, which plays a role in the regulation of various bodily functions such as growth and development, metabolism, and reproductive processes.

CACNA1H is also of interest as a potential drug target. Its role in the regulation of muscle contractions and other physiological processes makes it a potential target for the development of new treatments for a variety of conditions. For example, CACNA1H has been shown to be involved in the regulation of muscle contractions in individuals with genetic disorders such as muscular dystrophy, and it is thought to be a potential target for the development of muscle-building drugs.

In addition to its potential use as a drug target, CACNA1H is also of interest as a biomarker. Its expression is regulated in a variety of tissues and conditions, which makes it a potential source of information about the health and function of those tissues. For example, the expression of CACNA1H has been shown to be regulated in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Overall, CACNA1H is a protein that is expressed in many different tissues and plays a role in the regulation of various physiological processes that are important for the proper functioning of the body. Its potential as a drug target and biomarker make it an attractive target for further research and development.

Protein Name: Calcium Voltage-gated Channel Subunit Alpha1 H

Functions: Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation (PubMed:9670923, PubMed:9930755, PubMed:27149520). T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle (Probable). They may also be involved in the modulation of firing patterns of neurons (PubMed:15048902). In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia (PubMed:25907736, PubMed:27729216)

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