GSTM5: A Potential Drug Target for Xenobiotics (G2949)

Target Name: GSTM5

NCBI ID: G2949

GSTM5

GSTM5: A Potential Drug Target for Xenobiotics

Glutathione S-alkyltransferase M5 (GSTM5) is a enzyme that plays a crucial role in the detoxification and metabolism of xenobiotics, such as polychlorinated biphenyls (PCBs) and other environmental pollutants. GSTM5 is a member of the GSTM family of enzymes, which are involved in the detoxification and metabolism of a wide variety of xenobiotics.

GSTM5 is expressed in many different tissues and cells in the body, including the liver, kidney, and intestine. It is involved in the metabolism of PCBs, which are environmental pollutants that can be found in a wide variety of foods, products, and waste streams. PCBs can cause a variety of health problems, including reproductive and developmental problems, and are considered potential human carcinogens.

GSTM5 is also involved in the detoxification of other xenobiotics, including polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs). These compounds are also found in a wide variety of foods and products, and can cause a variety of health problems, including cancer.

GSTM5 is a potential drug target because of its involvement in the detoxification and metabolism of xenobiotics. Many of these compounds are considered potential human carcinogens, and GSTM5 may be a key enzyme in their metabolism. Additionally, GSTM5 may also be involved in the regulation of other pathways that are involved in the detoxification and metabolism of xenobiotics, such as the detoxification of aryl hydrocarbons (AHAs) and the metabolism of polycyclic aromatic hydrocarbons (PAHs).

GSTM5 may also be a potential biomarker for the detection and monitoring of exposure to xenobiotics. The detoxification of xenobiotics can cause a variety of symptoms and health problems, including fatigue, skin rash, and muscle weakness. GSTM5 may be a useful biomarker for detecting these symptoms and tracking the progress of exposure to xenobiotics.

In addition to its potential as a drug target and biomarker, GSTM5 is also of interest as a potential therapeutic approach for the detoxification and management of xenobiotics. Many of these compounds are toxic and can cause a variety of health problems, including cancer. GSTM5 may be a key enzyme in the detoxification and metabolism of these compounds, and targeting GSTM5 may be a promising strategy for the development of new treatments for a variety of xenobiotics-related diseases.

Overall, GSTM5 is a complex enzyme that is involved in the detoxification and metabolism of a wide variety of xenobiotics. As a potential drug target and biomarker, GSTM5 may be a valuable tool for the development of new treatments for a variety of xenobiotics-related diseases. Further research is needed to fully understand the role of GSTM5 in the detoxification and metabolism of xenobiotics, and to develop new strategies for the treatment of these conditions.

Protein Name: Glutathione S-transferase Mu 5

Functions: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles

The "GSTM5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSTM5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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