DGUOK: A Drug Target / Disease Biomarker (G1716)

Target Name: DGUOK

NCBI ID: G1716

DGUOK

DGUOK: A Drug Target / Disease Biomarker

DGUOK (Dopamine-Glu-Ulu-Ketone) is a molecule that has been identified as a potential drug target and biomarker for various neurological and psychiatric disorders. Its unique structure, which consists of a carbon loop and a carbon chain, has led to a high degree of structural complexity and a diverse range of biological functions.

The carbon loop of DGUOK has been shown to play a crucial role in its unique structure and function. The loop is composed of a series of nitrogen atoms and is connected to the carbon chain through a sulfur atom. This nitrogen-containing loop is the central binding site for DGUOK, and its unique structure allows it to interact with various molecules in the brain.

One of the key functions of DGUOK is its ability to modulate the activity of dopamine receptors in the brain. Dopamine is a neurotransmitter that plays a crucial role in the brain, and it is involved in a wide range of cognitive and behavioral processes. DGUOK has been shown to interact with dopamine receptors and regulate the activity of these receptors, which may have potential implications for the treatment of neurological and psychiatric disorders.

In addition to its role in modulating dopamine receptor activity, DGUOK has also been shown to play a role in the regulation of other signaling pathways in the brain. For example, DGUOK has been shown to interact with the protein TrkB, which is involved in the regulation of neurotransmitter release. This interaction may have implications for the treatment of disorders that are characterized by hyperactivity or impulsivity, such as attention deficit hyperactivity disorder (ADHD).

The high degree of structural complexity and the diverse range of biological functions of DGUOK also make it an attractive target for drug development. The synthesis and characterization of DGUOK have been optimized, and various studies have demonstrated its effectiveness in a wide range of cellular and animal models. For example, DGUOK has been shown to be a potent modulator of dopamine receptor activity, with potential implications for the treatment of disorders characterized by low dopamine levels, such as depression.

In conclusion, DGUOK is a structurally unique and functionally diverse molecule that has the potential to be a drug target and biomarker for a wide range of neurological and psychiatric disorders. Its unique structure and diverse biological functions make it an attractive target for further study and development as a therapeutic agent.

Protein Name: Deoxyguanosine Kinase

Functions: Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine (PubMed:8692979, PubMed:8706825, PubMed:11687801, PubMed:17073823, PubMed:23043144). In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs (By similarity). Widely used as target of antiviral and chemotherapeutic agents

The "DGUOK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DGUOK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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