ACKR1: A Protein Interacting with T-cell Receptor Alpha Chain

Target Name: ACKR1

NCBI ID: G2532

ACKR1

ACKR1: A Protein Interacting with T-cell Receptor Alpha Chain

ACKR1 (WBCQ1) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the T-cell receptor (TCR) family and is involved in the immune response.

ACKR1 has been identified as a potential drug target in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has been explored in various studies, and its potential as a drug has been discussed in the scientific community.

One of the key features of ACKR1 is its ability to interact with other proteins, including the T-cell receptor alpha chain (TCR伪). This interaction between ACKR1 and TCR伪 is critical for the function of the TCR, as it allows the TCR to recognize and respond to foreign substances in the body.

ACKR1 has also been shown to play a role in regulating the activity of immune cells, including T cells and natural killer cells. It has been shown to inhibit the activity of T-cells that are able to recognize and react to foreign substances, as well as to promote the activity of immune cells that are able to recognize and respond to foreign substances.

In addition to its role in the immune response, ACKR1 has also been shown to play a role in various other processes in the body. For example, it has been shown to be involved in the regulation of cell growth, cell death, and cell signaling. It has also been shown to play a role in the regulation of inflammation, as well as in the regulation of blood pressure.

ACKR1 has been shown to be a potential drug target in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has been explored in various studies, and its potential as a drug has been discussed in the scientific community.

One of the key features of ACKR1 is its ability to interact with other proteins, including the T-cell receptor alpha chain (TCR伪). This interaction between ACKR1 and TCR伪 is critical for the function of the TCR, as it allows the TCR to recognize and respond to foreign substances in the body.

ACKR1 has also been shown to play a role in regulating the activity of immune cells, including T cells and natural killer cells. It has been shown to inhibit the activity of T-cells that are able to recognize and react to foreign substances, as well as to promote the activity of immune cells that are able to recognize and respond to foreign substances.

In addition to its role in the immune response, ACKR1 has also been shown to play a role in various other processes in the body. For example, it has been shown to be involved in the regulation of cell growth, cell death, and cell signaling. It has also been shown to play a role in the regulation of inflammation, as well as in the regulation of blood pressure.

ACKR1 has been shown to be a potential drug target in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has been explored in various studies, and its potential as a drug has been discussed in the scientific community.

ACKR1 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the T-cell receptor (TCR) family and is involved in the immune response. Its role in the immune response is played by its ability to interact with other proteins, including the T-cell receptor alpha chain (TCR伪).

ACKR1 has also been shown to play a role in regulating the activity of immune cells, including T cells and natural killer cells. It has been shown to inhibit the activity of T-cells that are able to recognize and react to foreign substances, as well as to promote the activity of immune cells that are able to recognize and respond to foreign substances.

In addition to its role in the immune response, ACKR1 has also been shown to play

Protein Name: Atypical Chemokine Receptor 1 (Duffy Blood Group)

Functions: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and also for the malaria parasites P.vivax and P.knowlesi. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels

The "ACKR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ACKR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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