SLC51B: A Protein Critical for Cell Membrane Transport (G123264)

Target Name: SLC51B

NCBI ID: G123264

SLC51B

SLC51B: A Protein Critical for Cell Membrane Transport

SLC51B (Solute Carrier Family 51 Subunit Beta) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It plays a critical role in the transport of a variety of molecules, including ions, nutrients, and waste products.

SLC51B is a member of the Solute Carrier Family 51, which is a well-known family of proteins that play a central role in the transport of solutes and other molecules across cell membranes. This family of proteins is composed of several subunits, of which SLC51B is one of the most well-studied.

SLC51B is a subunit of the beta subunit of the SLC51 family. This subunit is responsible for the transport of various molecules, including glucose, glutamate, and other amino acids. It is expressed in a variety of tissues, including the brain, heart, and kidneys, and is involved in the regulation of a wide range of physiological processes.

One of the key functions of SLC51B is its role in the regulation of glucose metabolism. Glucose is an essential sugar that is used by the body for energy, and its levels must be carefully regulated in order to maintain proper cellular function. SLC51B is involved in the transport of glucose across cell membranes, and is therefore critical for the efficient exchange of glucose between the inside and outside of cells.

In addition to its role in glucose metabolism, SLC51B is also involved in the regulation of other physiological processes. For example, it is involved in the transport of amino acids, which are essential for the growth and development of tissues. It is also involved in the regulation of ion channels, which are responsible for the flow of electrical current through cell membranes.

SLC51B is also a potential drug target. The development of new treatments for diabetes and other conditions often involves targeting the transport of specific molecules across cell membranes. By inhibiting the activity of SLC51B, researchers may be able to block the transport of glucose and other molecules across cell membranes, which could be useful for treating conditions such as diabetes.

In conclusion, SLC51B (Solute Carrier Family 51 Subunit Beta) is a protein that plays a critical role in the transport of various molecules across cell membranes. Its regulation of glucose metabolism and other physiological processes makes it an important target for the development of new treatments for a variety of conditions. Further research is needed to fully understand the role of SLC51B in the regulation of cellular processes and its potential as a drug target.

Protein Name: Solute Carrier Family 51 Subunit Beta

Functions: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:16317684). Modulates SLC51A glycosylation, membrane trafficking and stability activities (PubMed:16317684). The Ost-alpha/Ost-beta complex efficiently transports the major species of bile acids (taurocholate) (PubMed:16317684). Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity). Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (PubMed:16317684). Able to transport eicosanoids such as prostaglandin E2 (By similarity)

The "SLC51B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC51B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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