Target Name: ZDHHC8
NCBI ID: G29801
Review Report on ZDHHC8 Target / Biomarker Content of Review Report on ZDHHC8 Target / Biomarker
ZDHHC8
Other Name(s): Palmitoyltransferase ZDHHC8 (isoform 2) | Zinc finger DHHC-type palmitoyltransferase 8, transcript variant 1 | Zinc finger, DHHC domain like containing 1 | ZDHHC8 variant 2 | Zinc finger DHHC domain-containing protein 8 | Membrane-associated DHHC8 zinc finger protein | zinc finger protein 378 | ZDHHC8 variant 1 | DHHC8 | Zinc finger, DHHC domain containing 8 | zinc finger, DHHC domain like containing 1 | zinc finger DHHC-type palmitoyltransferase 8 | ZNF378 | zinc finger DHHC-type containing 8 | DHHC-8 | Palmitoyltransferase ZDHHC8 (isoform 1) | Palmitoyltransferase ZDHHC8 | ZDHHCL1 | ZDHC8_HUMAN | Zinc finger protein 378 | Zinc finger DHHC-type palmitoyltransferase 8, transcript variant 2 | membrane-associated DHHC8 zinc finger protein

Understanding ZDHHC8: A Potential Drug Target and Biomarker

ZDHHC8 (Palmitoyltransferase ZDHHC8 (isoform 2)) is a protein that is expressed in various tissues and organs in the body. It is a member of the ZDHHC family of proteins, which are involved in the transfer of palmitoyl groups from the palmitoyl precursor to target Protein. One of the unique aspects of ZDHHC8 is its isoform, which refers to one of the different forms of the protein that exist in the cell.

The ZDHHC8 protein is involved in the transfer of palmitoyl groups from the palmitoyl precursor to various target proteins. This process is critical for the regulation of cellular signaling pathways and is a key step in the development and maintenance of various tissues and organs.

ZDHHC8 is also involved in the regulation of cellular metabolism and has been shown to play a role in the metabolism of muscle, bone, and other tissues. It has been shown to promote muscle growth and to regulate muscle protein synthesis, which is important for muscle development and maintenance.

In addition to its role in cellular signaling and metabolism, ZDHHC8 is also involved in the regulation of cellular inflammation. It has been shown to play a role in the regulation of inflammation and has been shown to have anti-inflammatory effects.

Given its involvement in so many cellular processes, ZDHHC8 is a promising drug target and has been shown to be a good candidate for intervention in a variety of diseases. For example, ZDHHC8 has been shown to be involved in the development and progression of various cancers. , including breast cancer and colon cancer. It has also been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential as a drug target, ZDHHC8 is also a potential biomarker for various diseases. Its involvement in the regulation of cellular signaling pathways and its role in the regulation of cellular metabolism make it an attractive candidate for use as a diagnostic or therapeutic target.

In conclusion, ZDHHC8 is a protein that is involved in a variety of cellular processes and has been shown to play a role in the development and progression of various diseases. Its potential as a drug target and biomarker make it an attractive candidate for further investigation and potential intervention in a variety of diseases. Further research is needed to fully understand the role of ZDHHC8 in cellular processes and its potential as a therapeutic or diagnostic agent.

Protein Name: Zinc Finger DHHC-type Palmitoyltransferase 8

Functions: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes (Probable). Through the palmitoylation of ABCA1 regulates the localization of the transporter to the plasma membrane and thereby regulates its function in cholesterol and phospholipid efflux (Probable). Could also pamitoylate the D(2) dopamine receptor DRD2 and regulate its stability and localization to the plasma membrane (Probable). Could also play a role in glutamatergic transmission (By similarity)

The "ZDHHC8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZDHHC8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ZDHHC8BP | ZDHHC9 | ZEB1 | ZEB1-AS1 | ZEB2 | ZEB2-AS1 | ZER1 | ZFAND1 | ZFAND2A | ZFAND2B | ZFAND3 | ZFAND4 | ZFAND5 | ZFAND6 | ZFAS1 | ZFAT | ZFAT-AS1 | ZFC3H1 | ZFHX2 | ZFHX3 | ZFHX4 | ZFHX4-AS1 | ZFP1 | ZFP14 | ZFP2 | ZFP28 | ZFP28-DT | ZFP3 | ZFP30 | ZFP36 | ZFP36L1 | ZFP36L2 | ZFP37 | ZFP41 | ZFP42 | ZFP57 | ZFP62 | ZFP64 | ZFP64P1 | ZFP69 | ZFP69B | ZFP82 | ZFP90 | ZFP91 | ZFP91-CNTF | ZFP92 | ZFPL1 | ZFPM1 | ZFPM2 | ZFPM2-AS1 | ZFR | ZFR2 | ZFTA | ZFTRAF1 | ZFX | ZFX-AS1 | ZFY | ZFYVE1 | ZFYVE16 | ZFYVE19 | ZFYVE21 | ZFYVE26 | ZFYVE27 | ZFYVE28 | ZFYVE9 | ZFYVE9P1 | ZG16 | ZG16B | ZGLP1 | ZGPAT | ZGRF1 | ZHX1 | ZHX1-C8orf76 | ZHX2 | ZHX3 | ZIC1 | ZIC2 | ZIC3 | ZIC4 | ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2