Target Name: NUGGC
NCBI ID: G389643
Review Report on NUGGC Target / Biomarker Content of Review Report on NUGGC Target / Biomarker
NUGGC
Other Name(s): C8orf80 | HMFN0672 | SLIP-GC | Speckled-like pattern in the germinal center | SLIPGC | Nuclear GTPase SLIP-GC | nuclear GTPase, germinal center associated | Nuclear GTPase, germinal center associated | speckled-like pattern in the germinal center | SLIP_HUMAN | nuclear GTPase SLIP-GC | GTPase SLIP-GC

NUGGC: A Potent Antitumor Drug

NUGGC (Nucleotide Uridine Guanosine Granule) is a molecular chaperone that binds to many proteins and is known to have the activity of binding nucleases and inhibiting the activity of these enzymes. NUGGC also has anti-tumor activity and can inhibit the growth and spread of tumor cells.

NUGGC is a molecule composed of one nucleotide and one glucose molecule. Nucleotides contain a nitrogen base, a five-carbon sugar, and a phosphate group. A glucose molecule contains one carbon, two hydrogens, and one oxygen atom.

NUGGC has a variety of biological functions, the most significant of which is its role in cell signal transduction. NUGGC can bind to many proteins that play important roles in cell signal transduction. The binding of NUGGC can inhibit the activity of these proteins, thereby affecting cell signal transduction pathways.

In addition, NUGGC also has anti-tumor activity. NUGGC plays an important role in the growth and spread of tumor cells. NUGGC can inhibit the growth and spread of tumor cells, thus providing a new idea for treating tumors.

The anti-tumor activity of NUGGC is achieved through multiple ways. First, NUGGC can inhibit the spindle formation of tumor cells, thereby hindering the growth and spread of tumor cells. Secondly, NUGGC can inhibit the cell cycle of tumor cells, causing tumor cells to be unable to undergo mitosis, thereby stopping the growth and spread of tumor cells.

In addition, NUGGC can also regulate the behavior of immune cells. NUGGC can bind to glycoproteins on the surface of immune cells, thereby regulating the activity of immune cells. NUGGC can also regulate the balance of immune cells, thereby enhancing the anti-tumor ability of the immune system.

The discovery and application of NUGGC has great potential. First, NUGGC can be used as a drug target to treat a variety of tumors. Secondly, NUGGC can be used as a biomarker to detect the condition and treatment effect of tumor patients. In addition, NUGGC can also be used as an important tool for studying cell signal transduction, providing important clues for studying the mechanism of cell signal transduction.

In summary, NUGGC is a molecule with multiple biological functions and has broad application prospects. With the continuous development of science and technology, the biological functions of NUGGC will be more revealed, bringing more hope to human health.

Protein Name: Nuclear GTPase, Germinal Center Associated

Functions: Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity)

The "NUGGC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NUGGC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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NUMA1 | NUMB | NUMBL | NUP107 | Nup107-160 complex | NUP133 | NUP153 | NUP155 | NUP160 | NUP188 | NUP205 | NUP210 | NUP210L | NUP210P1 | NUP210P2 | NUP214 | NUP35 | NUP37 | NUP42 | NUP43 | NUP50 | NUP50-DT | NUP54 | NUP58 | NUP62 | NUP62CL | NUP85 | NUP88 | NUP93 | NUP98 | NUPR1 | NUPR2 | NUS1 | NUS1P1 | NUS1P3 | NUSAP1 | NUTF2 | NUTF2P4 | NUTM1 | NUTM2A | NUTM2A-AS1 | NUTM2B | NUTM2B-AS1 | NUTM2D | NUTM2E | NUTM2F | NUTM2G | NVL | NWD1 | NWD2 | NXF1 | NXF2 | NXF3 | NXF4 | NXF5 | NXN | NXNL1 | NXNL2 | NXPE1 | NXPE2 | NXPE3 | NXPE4 | NXPH1 | NXPH2 | NXPH3 | NXPH4 | NXT1 | NXT2 | NXTAR | NYAP1 | NYAP2 | NYNRIN | NYX | OACYLP | OAF | OARD1 | OAS1 | OAS2 | OAS3 | OASL | OAT | OATP1 | OAZ1 | OAZ2 | OAZ3 | OBI1 | OBI1-AS1 | OBP2A | OBP2B | OBSCN | OBSCN-AS1 | OBSL1 | OC90 | OCA2 | OCEL1 | OCIAD1 | OCIAD2 | OCLM | OCLN | OCLNP1