CFAP77: A Potential Drug Target Or Biomarker (G389799)

Target Name: CFAP77

NCBI ID: G389799

CFAP77

CFAP77: A Potential Drug Target Or Biomarker

CFAP77 (CFA77_HUMAN), a protein that belongs to the superfamily of cytoplasmic fusion proteins, has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug or biomarker has generated a great deal of interest in the scientific community.

CFAP77 is a 21-kDa protein that is expressed in most tissues of the body, including the brain, heart, liver, and pancreas. It is composed of 156 amino acid residues and has a molecular weight of 19.9 kDa. CFAP77 is involved in various cellular processes, including cell adhesion, migration, and invasion. It plays a critical role in the development and maintenance of tissues, including the nervous system and the immune system.

One of the most significant functions of CFAP77 is its role in cell adhesion. CFAP77 is a critical protein for the formation of tight junctions, which are the main barrier between cells in the tissue and allow for the exchange of nutrients and waste products. tight junctions are also involved in the regulation of cell-cell communication and play a crucial role in the development and maintenance of tissues, including the nervous system and the immune system.

CFAP77 is also involved in the regulation of cell migration and invasion. It plays a critical role in the migration of neurons and other cell types to their final destinations in the developing nervous system, and it is also involved in the regulation of the invasive properties of cancer cells.

In addition to its role in cell adhesion and migration, CFAP77 is also involved in the regulation of various cellular processes that are essential for the survival of cells. It plays a critical role in the regulation of cell cycle progression, and it is involved in the regulation of DNA replication and gene expression. CFAP77 is also involved in the regulation of cell signaling pathways, including the TGF-β pathway, which is involved in the regulation of cell growth, differentiation, and survival.

CFAP77 is also a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its expression has been observed in a variety of cancer types, including breast, ovarian, and colorectal cancer. It is also involved in the regulation of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In addition, CFAP77 has been shown to be involved in the regulation of autoimmune disorders, including rheumatoid arthritis and multiple sclerosis.

CFAP77 has also been shown to have potential as a drug target. Its unique structure and function make it an attractive target for small molecules, antibodies, and other therapeutic agents. Several studies have shown that CFAP77 can be inhibited by small molecules, antibodies, and other therapeutic agents, and that these inhibitors have potential therapeutic applications in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

CFAP77 has also been shown to have potential as a biomarker for monitoring the effectiveness of therapeutic agents. Its expression can be monitored using techniques such as Western blotting, immunofluorescence, and RNA sequencing, and these methods can be used to assess the efficacy of different therapeutic agents.

In conclusion, CFAP77 is a protein that is involved in various cellular processes that are essential for the survival and development of cells. Its unique structure and function make it an attractive target for research into its potential as a drug or biomarker. Further studies are needed to fully understand its functions and its potential as a therapeutic agent.

Protein Name: Cilia And Flagella Associated Protein 77

The "CFAP77 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CFAP77 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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